Enzyme Inhibition
MATHEMATICAL For the following aspartase reaction (see Question 28) in the presence of the inhibitor hydroxymethylaspartate, determine KM and whether the inhibition is competitive or noncompetitive.
[S] (molarity) | V, No inhibitor (arbitrary units) | V, inhibitor Present (same arbitrary units) |
1 × 1024 | 0.026 | 0.010 |
5 × 1024 | 0.092 | 0.040 |
1.5 × 10“3 | 0.136 | 0.086 |
2.5 × 10“3 | 0.150 | 0.120 |
5 × 10“3 | 0.165 | 0.142 |
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