Below are shown two views of the backbone representation of the Myc-Max complex binding to DNA (PDB ID: 1NPK). Myc and Max are members of the basic helix-loop-helix (bHLH) class of DNA-binding proteins (see Chapter 29). Myc (red) and Max (blue) associate via a coiled-coil interaction and bind DNA as a dimer.
(a) Are the helices bound to the DNA likely to be amphiphihe? Explain.
(b) Where do you predict the N- and C-termini are located for Max?
We need at least 10 more requests to produce the solution.
0 / 10 have requested this problem solution
The more requests, the faster the answer.