In this and following chapter’s, more difficult problems are indicated by an asterisk.
The amino acid arginine ionizes according to the scheme below:
(a) Calculate the isoelectric point of arginine. You can neglect contributions from form I. Why?
(b) Calculate the average charge on arginine when pH = 9.20 (Hint: find the average charge for each ionizable group and sum these together; see Table 2.8 for some guidance).
(c) Is the value of average charge you calculated in part (b) reasonable, given the pI you calculated in part (a)? Explain your answer.
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