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As part of the “Problems and Discussion Questions” section in this and each subsequent cha...

As part of the Problems and Discussion Questions section in this and each subsequent chapter, we shall present a number of ExtraSpicy genetics problems. We have chosen to set these apart in order to identify problems that are particularly challenging. You may be asked to examine and assess actual data, to design genetics experiments, or to engage in cooperative learning. Like genetic varieties of peppers, some of these experiences are just spicy and some are very hot. We hope that you will enjoy the challenges that they pose.

An interesting procedure has been applied for assessing the chromosomal balance of potential secondary oocytes for use in human in vitro fertilization. Using fluorescence in situ hybridization (FISH), Kuliev and Verlinsky (2004) were able to identify individual chromosomes in first polar bodies and thereby infer the chromosomal makeup of “sister” oocytes. Assume that when examining a first polar body you saw that it had one copy (dyad) of each chromosome but two dyads of chromosome 21. What would you expect to be the chromosomal 21 complement in the secondary oocyte? What consequences are likely in the resulting zygote, if the secondary oocyte was fertilized?

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