Question 4 (5 points) OCH + NOCH NaOCH, CH,OH A B CH,OH The following synthetic scheme...
What is the major product obtained from the following reaction: OCH Br NaOCH OCH CH OH BI OCH, 0 1 2 3 What is the major organic product obtained from the following reaction (KOtBu = OC(CH3)31 big bulky base)? 0-Bu 2 KOBU BUCH 0.tBu W08 0-Bu 1 2 3 0 4
predict the products of the following reactions 0 () CH,CH CCH,-C-OCH, NocCH (2) CH (3) Ho .heat (I) NaOCH2CH (2) H,O', heat (b) CH,-C-CH-C-OCH,CH,+ CH, (1) LDA -OH (c) Ph CH, () CH,CH,CH,Br (1) H2C-CH CH,Br (2) H0* OCH, NaOCH Ph (2) CH,CH,CH2CH2Br (g) product from part (f) (decarboxylation) 0 () CH,CH CCH,-C-OCH, NocCH (2) CH (3) Ho .heat (I) NaOCH2CH (2) H,O', heat (b) CH,-C-CH-C-OCH,CH,+ CH, (1) LDA -OH (c) Ph CH, () CH,CH,CH,Br (1) H2C-CH CH,Br (2) H0*...
Question 24 Predict the product(s) for the following reaction. CH,OH/H 504 OCH OH OCH OH HO нусо HECO HO I II III IV От O II III O IV o none of these MacBook Air
Question 4 (14 points) Propose a synthesis. You may use any reagents you wish. H2 Question 5. (15 points). Perform a Robinson Annulation on the following reagents, showing full formal arrow-pushing. Be sure to end as a ketone! Clearly indicate your product in your answer. You may use any reagents you wish. NH2 Question 6. (20 points) Draw the following reagent in its most stable chair form. Show your process to ensure partial credit. CHO HO OH HO OH CH,OH
10. Please Check 1 by 1 and read carefully. I would need a perfect score for this . Thanks Select the keyword or phrase that will best complete each sentence A Claisen reaction is a nucleophilic substitution in which an enolate is the nucleophile Key terms: Robinson annulation Aldol condensation: An aldol reaction in which the initially formed p hydroxyl carbonyl compound loses water by dehydration. Claisen reaction Aldol condensation Dieckmann reaction: An intramolecular Claisen reaction of a diester to...
5. Propose mechanisms for the following reactions (20 points) 1. CH3MgBr OCH CH2HO + CH CH OH
1. (20 Points) In the following synthetic scheme there are four reaction steps labeled (1-4). Some of the reaction steps will proceed as shown (correct) and other steps are incorrect. Consider each labeled step as separately. a. Label cach step as either correct or incorrect. b. For the steps labeled incorrect, either no reaction occurs or the wrong product is shown. In one sentence, explain why the step is incorrect. Provide the correct product structure (or outcome). ran o
1. (20 Points) In the following synthetic scheme there are four reaction steps labeled (1-4). Some of the reaction steps will proceed as shown (correct) and other steps are incorrect. Consider each labeled step as separately. a. Label each step as either correct or incorrect. b. For the steps labeled incorrect, either no reaction occurs or the wrong product is shown. In one sentence, explain why the step is incorrect. Provide the correct product structure (or outcome). 1. Nah 2...
11. (14 pts) Draw the major product of the following synthetic scheme. A) 1. NaH/2.CH,CH,Br B) 1. CHLI/2.4,0 C) 1. NaH/2. CH!
Question: What is the major product for the following sequence of reactions? OH 1. HOCH,CH,OH, H,O 2. TMSCI 3. NaOCH, 4.H,0 OTMS OTMS