Question

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10 CHAPTER 6 Genetic and Developmental Diseases 3. A woman with epilepsy would like to become pregnant but is worried about the potentially teratogenic effects of the antiepileptic drugs she is taking. Which of the following is true regarding her medications? A. The risk of harmful effects is greatest in the first 16 weeks of pregnancy B. Pharmaceutical drugs for epilepsy cur rently on the market are safe to use during pregnancy An epileptic seizure will be more harmful to the fetus than taking these drugs D. The drugs are more likely to cause chromo- somal abnormalities than to interfere with the development of the embryo or the fetus. E. Pharmaceutical drugs do not cross the pla- centa and therefore will not harm the embryo or fetus. 4. Amniocentesis is performed in order to do which of the following tests? A Quad test B. Karyotyping C. Testing for phenylketonuria D. Whole genome sequencing 5. During which period of development does eryth- roblastosis fetalis develop? A. Embryonal B. Fetal C. Infancy D. Childhood 6. Many patients with monogenetic diseases, such as sickle cell anemia and cystic fibrosis, survive for much longer today than they did a few decades ago. What is the reason for this? A. The exact genetic abnormality is known and can be repaired. B. The product of the defective gene can be artifi- cially synthesized and administered to patients. C. The diseases are becoming less virulent. D. There are better techniques for prevention and management of complications. 7. The most important cause of disease in the peri- natal period is A. chromosomal disorders. B. congenital heart defect. C. prematurity. D. maternal nutritional status. 8. Chorioamnionitis most commonly results A congenital birth defects such as clef palate. B. premature delivery. C ataracts, auditory deficiency, and me retardation D. genetic diseases. E erythroblastosis fetalls. 9. A family is being counseled for a possible disease. On the mother's side of the family uncles and nephews have manifested symptom and one aunt passed away in early adolesce Two of the couple's four children, both he are showing evidence of the disease. There history of its occurrence on the father's wide the family. As the genetic counselor, you are su pecting that the disease is transmitted in wh fashion? A. Autosomal dominant B. Autosomal recessive C. Mitochondrial D. Sex-linked 10. The fetal period is defined as A. the time from fertilization to birth. B. the last month of intrauterine development. C. the eighth week of fertilization to birth. D. the first 4 weeks after fertilization. Which of the following is not an effect of infec. tion during development? A. Teratogenic insults to central nervous system B. Premature birth due to chorioamnionitis C. Frequent illness in first 2 years of life D. Increased birth weight and neonatal hypoglycemia Causes of low birth weight include all of the cllowing except . Maternal nutrition. B. Prematurity. Maternal hypertension. Phenylketonuria. Which of the following is an example of non- Mendelian inheritance? A. Klinefelter syndrome B. Hemosiderosis C. Mitochondrial disorders D. Erythroblastosis fetalis Reference 1. Johnson M Gallagher K One in billion a hole life

Answer 1

3- Answer is A.Maximum risk of harmful effects is in the first trimester of the pregnancy.

4- Amniocentesis is performed for karyotyping.

5- Eythroblastosis fetalis develops in infancy.

6- There are better techniques for prevention and management of complications.