Medical researchers conduct a clinical trial of a new drug designed to lower cholesterol. They determine that there is a 0.27 probability that their results could occur by chance. Based on that probability value
The probability that their results could occur by chance is 0.27. Thus the p-value (probability that the observed difference would happen if the null hypothesis of no difference between new and old drug was true) of the test is 0.27. As, p-value is greater than the significance level of 0.05, the chance will be ruled out as a reasonable explanation that the new drug designed to lower cholesterol.
Medical researchers conduct a clinical trial of a new drug designed to lower cholesterol. They determine...
A clinical trial was designed to compare a new drug for lowering cholesterol to a placebo. The 100 subjects who took the new drug had a mean cholesterol of 180.5 with a standard deviation of 23.3. The 100 subjects who took the placebo had a mean cholesterol of 204.1 with a standard deviation of 22.1. Construct a two-sided 95% confidence interval for the difference between the two means, assuming equal variance. Give an interpretation of the confidence interval. You MUST...
Investigators want to determine the effectiveness of a new drug in lowering cholesterol. They conduct a small clinical trial in which patients were randomized to receive the new drug or placebo. The total cholesterol was measured after ten weeks on the assigned treatment. The table below shows the results. Sample size (n) Mean Clostrol SD New drug 30 198.8 26.7 Placebo 30 215.4 30.3 Is there sufficient evidence to conclude a difference in mean cholesterol for patients on the...
1) Investigators want to determine the effectiveness of a new drug in lowering cholesterol. They conduct a small clinical trial in which patients were randomized to receive the new drug or placebo. The total cholesterol was measured after ten weeks on the assigned treatment. The table below shows the results. Sample Size (n) Mean Cholesterol SD New drug 30 198.8 26.7 Placebo 30 215.4 30.3 Is there sufficient evidence to conclude a difference in mean cholesterol for patients on the...
The drug lipitor is meant to lower cholesterol levels. In a clinical trial of 863 patients who received 10 mg doses of lipitor daily, 47 reported a headache as a side effect. Assuming that more than 50,000 take lipitor, obtain a 99% confidence interval for the proportion of patients who reported a headache. Interpret the interval.
The relative risk (RR) associated with the new cholesterol-lowering drug was: A randomised controlled trial was designed to test the effectiveness of a new cholesterol-lowering drug on the incidence of heart attacks in obese people with diabetes and heart disease. The published results reported the following: 1. an cumulative incidence of heart attacks in those taking the new drug of 3.3% 2. an cumulative incidence of heart attacks in those NOT taking the new drug of 5.5%.
6. A clinical trial is being planned to investigate the effect of a new experimental drug designed to reduce total serum cholesterol. Investigators will enroll participants with total cholesterol levels between 200-240, they will be randomized to receive the new drug or a placebo and followed for 2 months, and the total cholesterol will be measured. Investigators plan to estimate a confidence interval with a difference of 8 points in mean total cholesterol levels between groups. They assume that 10%...
3. Consider a Phase II clinical trial designed to investigate the effectiveness of a new drug to reduce symptoms of asthma in children. A total of n=10 participants are randomized to receive either the new drug or a placebo. Participants are asked to record the number of episodes of shortness of breath over a 1 week period following receipt of the assigned treatment. The data are shown below. Placebo: 7, 2, 10, 5, 12 New Drug: 3, 6, 4, 11,...
(1 point) A new drug to lower total cholesterol is being tested. A study is designed to evaluate the efficacy of the drug. Sixteen patients agree to participate in the study and each is asked to take the new drug for 4 weeks. Before starting the treatment, each patient's total cholesterol level is measured. After taking the drug for 4 weeks, each patient's total cholesterol level is measured again. The 99% confidence interval for the change in total cholesterol (After...
A group of researchers are interested in conducting a clinical trial to determine whether a new drug was useful in preventing diabetes. They identified 346 potential participants for the trial. At the end of the clinical exam, 22 were discovered to have diabetes. The remaining subjects entered the trial and were divided equally into treatment and placebo groups. Of those in the treatment group, 56 developed diabetes after 4 years follow-up while 79 during the same period in the placebo...
a group of of researchers are interested in conducting a
clinical trial to determine whether a new cholesterol lowering
agent was useful in preventing coronary heart disease (CHD). They
identified 14,327 potential participants for the trial. At the
intinial clincal exam 422 were discovered to have CHD. The
remaining subjects entered the trial and were divided into the
treatment and placebo groups. Of those in the treatment group, 535
develop CHD after 5 years of follow up while 568 developed...