a) A patient is found to have a urine flow rate of 1 ml/min, a plasma...
a) A patient is found to have a urine flow rate of 1 ml/min, a plasma urea concentration of 20 mg/100 ml, and a urinary urea concentration of 1000 mg/100 ml. Calculate the specific plasma clearance of urea for this individual.
b)What is the relative plasma clearance of urea for the patient in “A” if GFR = 75 ml/min? Does the patient reabsorb or secrete urea? How can you tell?
Homework Answers
a) specific plasma clearance of urea: cm= U×V/P
Cm- Maximum urea clearance.
U- Urea concentration in urine = 1000mg/100ml,
that is, 10mg/1ml
V- Urea excreted per minute per ml. 75ml/minute
P- Urine concentration in plasma. 20mg/100ml
That is, 0.2mg/ ml
Cm= 10×75/0.2
= 750/0.2
= 32.5
Maximum area clearance 32.5.
B) Normal GFR rate= more than 90ml / minutes
If its 75ml/ minutes indicates plasma clearance of patient is reduced.
Urea reabsorption is reduced.
Its indicated by GFR rate
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