Choose the reaction that is least likely to undergo an Sn2 reaction pathway. Question 1 A...
Workshop Quiz 10-Substitution and elimination 1. Choose the reaction that is least likely to undergo an SN2 reaction pathway. CH.он A NaNg CH3CN NaCN Hас— CN HyC C DMF NaSCH3 D OTs acetone Nal OMs acetone Choose the reaction that is least likely to undergo an E2 reaction pathwa 2. NAOCH3 CH-оH
Choose the reaction that is least likely to undergo an E2 reaction pathway. Question 2 NaOCH3 CH,он Br O он В кос(сH,) нос(CH,) Br D NaC CH CH2CN кос(CH) C НОС(CH,)з D O C O E Enter Your Answer: OA (R)-1-bromo-2-methylbutane undergoes substitution when reacted with sodium iodide (NaI) in acetone. Choose the major product obtained from this reaction. Question 3 A (R)-1-iodo-2-methyl butane B (S)-1-iodo-2-methylbutane C racemic 1-iodo-2- methylbutane D (R)-1-bromo-2-iodobutane E (S)-1-bromo-2-iodobutane F (S)-1-sodium-2-methylbutane A B F F...
Q1. Identify the reaction mechanism most likely to take place (E1, SN1, E2, SN2 or a combination of these) in each of the following cases. Draw the major product(s), include stereochemistry when relevant. Br -OtBu Br NaCN, DMF → CI Носна 1. Nal/acetone 2. NaCN/DMF NaoMe H2SO4 OH Lyon CN (CH3)2CO CI NaOH →
Question 9 (2 points) Which of the following carbocations is (are) likely to undergo rearrangement through a methyl shift? HC CH HC CH H₃C. CH INI a) both I and II b) both II and III OI d) 1 Question 10 (2 points) Choose a major product for the reaction below 0 Cl/AICI OCH, CI OCH OCH OCH a) I, II and Ill b) d)
Question 1: Determine whether each substitution reaction shown below is likely to proceed by an Snl or Sy2 mechanism and explain your reasoning a) Br + NaOCH3 acetone b) C(CH3)3CI ethanol OTS c) + NaN3 DMSO
Which statement or set of conditions listed below is not consistent with an Syl reaction pathway? O a. Neutral nucleophile work just fine. b. The leaving group is typically the conjugate base of a strong acid. O c. The rate is not dependent upon the concentration of the nucleophile. d. The temperature is relatively "cooler" to reduce competing elimination products. e. The solvent is polar and aprotic. Of. The substrate has a leaving group that is typically on a 30,...
30. Late papers not accepted. Work Independently. 1. Predict the most likely reaction mechanism (SN1, SN2, E1, E2) and draw all products. CH₂ Na O=CH₂ Hic Br 2 Draw complete mechanism with arrows for the SNI/E1 mechanism. Check for carbocation rearrangements CH3 + H2O 3. Which is the major product for the following reaction? Y CH + NaOH CH HO HO H₃ CH₂ H₃ HOCH CH₂ H₃ CHE CH₂ CH₂ CH3 CH 4. Name the following including the R/S, E/Z...
Choose the most stable conformation of the major product of the following reaction. Question 1 soc ? pyridine OH F Enter Your Answer: OC O D OE OF OA Select the order that has the following anions correctly arranged with respect to increasing stability. Question 2 2 3 AJ ng Enter Your Answer: OA OB Oc OD OE OF Select the synthetic pathway(s) that would form 3-methyl- 4-nonyne as the major product Question 3 3methyl4nonyne Na NaH Na D.1& I...
Consider the SN2 reaction of butyl bromide with hydroxide ion , Assuming no other changes, what effect on the reaction rate would result from simultaneously doubling the concentrations of both butyl bromide and hydroxyl ion No effect (B)It would double the rate (C)it would increase the rate six times (D) It would increase the rate four times. 2. Which alky halide would you expect to undergo SN1 hydrolysis most rapidly? (A) (CH3)3C-I (B) (CH3)3C-Br (C) (CH3)3C-Cl (D) (CH3)3C-F 3....
_1. An alkyl halide which might be expected to undergo rearrangement under Snl or E1 conditions is: HZC Br CH3 A. 1 B. | F—CH,BH C. CH3-C-CH-CH, CHz CH3 D. CH3 CH3-C-CH2CH2-Br CH3 E. A Br 2. Your task is to convert 2-chloropentane into 1-pentene. Which reagents would you choose? a) NaOH/H20 b) KOH/CH3OH c) CH3ONa/CH3OH d) CH3CH2ONa/CH3CH2OH e) (CH3)3COK/(CH3)3COH 3. Circle the reaction below which is faster in polar protic solvents. OH,H,O A. CH,CH,CH,Br- CH,CH,CH,OH + Br or SH.RSH...