Question Acic charge Which of the following would be mostly uncharged at pH 7.4? A Naproxen...

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Answer 1

Answer #1

answer is B

according to henderson hasselbalch equation

pH=pka + log(conjugated base)/(weak acid)

by substituting the value for pH and pka the value of diphenhydramine is lesser than other option HENCE it is mostly likely to remain unchanged.

also higher the pka,the weaker the acid and lesser the ability to donate proton in aqueous solution .

Answer 2

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