1. For each of the following reactions, write S if it is a substitution and E...
2. Predict which reactions proceeded by an SN1, SN2, El or E2 mechanism: NaOCH-CHa Br оСнCH +NaBr носH-Cнь 50° b. +NaCi Nal DMSO, 45° NaOCHa NaBr +HOCH носн, 100° но +HI acetone, 50 HSO +H2O H2O, 120 кос(CHa +KBr +HOC(CHals НоС(CHа, 100°С но DMSO, 40° +HI HCIZNCI2 +H2O h. H,O, 45° CH OH +HCI H2O, 100
please answer all Chemistry 420 1. For each of the following reactions, write S if it is a substitution and E if it is an elimination. Also write R for all of those that are also rearrangements. w = 8 2. Predict which reactions proceeded by an SI, SN2. El or E2 mechanism: NHOCHCH, OCH CHg+NaBr HOCH, CH, 50° + Naci Nal DMSO, 45° NaOCH +NaBr + HOCH HOCH, 100° H2O + HI acetone, 50° HO HOSO Hy0, 120° xha...
1. for each of thenfollowing write S if it is substitue and E if it is elimination. also write R for those that are rearrangement 2. predict which reactions proceed by SN1 SN2 E1 or E2 mechanism 10/2ery due MON Unit 3 HW#2 Chemistry 420 wo Name: 1. For each of the following reactions, write S if it is a substitution and E if it is an elimination. Also write R for all of those that are also rearrangements. +...
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
Practice Problems on S, S2 E1 &E2 1. Describe the ollowing chemical reactions as Sl, S2, El & E Draw a curved arow mechanim for each resction CHCHO N ethanol NaSH DMSO SH Кон но DMSO NaNH2 NH3 отв NH3 HN TsO TsO CH CHg Nal CHs acetone
Unit 3 Hinw '3 SNİSNDELE2 1. Give the major product(s) for the following reactions. Indicate the mec reaction occurs, write "no reaction. s) in operation. If no KOC(CH) (CH COH b. H3C NaNH2 NHy Nal H3C H2CH-CH3 CH,COCH CH OH CH3 2. Give the mechanism of each of the following reactions. NaCN CH CH CHCN NaBr a. CH,CH,CH Br acetone HSCH,CH (CH) CSCH,CH3 HBr Cl + NaCI + CH OH NaOCH CH3OH Br CH OH CH3
7. Predict the product(s) of each of the following reactions include stereochemistry where important and indicate the mechanism (S, S,2, El, E2). 80°C a 2-chloro-2-methylbutane NaOH Н.о b. (R)-2-chloropentane Nac c-H DMSO с1 (снс. Cн, CH,ОН d. trans-1-chloro-3-methylcyclohexane+ NaOC(CH) e. 2-chloro-3-phenylbutane Н.о f. trans-1-bromo-3-methyleyclopentane Nal acetone NaOCH THон g 2-chloro-2-methylbutane EIOH h R-3-bromo-2-methylpentane . trans-1-bromo-2-isopropyleyclohexane CHCOK NaSH Н,о j. 1-bromopropaе NaOCH снон CH коссH). I-bromobutane m. cis-1-chloro-3-methyleyclobutane Nal DMSO сHсH,он n. (R)-2-iodo-2-phenylethane NaOH o. 1-iodobutane p. 2-bromo-3-methylbutane KOC(CH). но (S)-3-chlorocyclopentene...
7. For the following substitution reactions predict the product(s) showing stereochemistry only if is of revelance. Also comment on what type reaction: S1 or SN2. Finally is the starting material and product optically active or inactive? Explain! CH, OH HBr CN CH3CH2CH3 HO HBr CN 1 CI CH3CH2CH3 НО HBr CH Br H3C
17. Draw the structure of the major organic product(s) for each of the following reactions. Indicate stereochemistry when appropriate. C(CH3)3 NASH Br (S)-2-bromononane - acetonitrile KOH CH,OH NaCN HE Br Acetonitrile C2H5 H, Br NaOH Acetone excess HBr ROOR HC1 + Br Na o DMSO
For each of the following reactions: (1) Draw all of the organic product(s) that would be formed, and (2) label each product as formed via S1, S2. E1, or E2. For elimination products, label as major or minor. Pay close attention to regiochemistry, stereochemistry, and whether carbocation rearrangements would occur. - DBN ci Br H20 B A C CH3OH acetone NaOH D Br DMSO