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MEDICATION CALCULATION #62 Order: cyclophosphamide (Cytoxan) 400 mg, IV, every week. Drug dose parameter: 350-550 mg...

MEDICATION CALCULATION #62

Order: cyclophosphamide (Cytoxan) 400 mg, IV, every week. Drug dose parameter: 350-550 mg / m2; client weight is 135 pounds & height is 63 inches

Available: Cytoxan (cyclophosphamide) 500 mg; Instruction: Dilute drug in 250 mL D5W & infuse in 1 hour.

a. How many mL of Cytoxan equals 400 mg?

b. Using macrodrip set with drop factor of 10 gtt/mL, the infursion rate should be _____ gtt/min?

c. Is the drug dose within safe parameters?

Please show your step by step calculations.

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Answer #1

The weight(135pounds)=61kg

Height(63")=160cm

Available drug=500mg

Diluted with 250ml

Each ml is 2mg

A) The ml of cytoxan which equals 400mg is 200ml.

B) using the drip factor of 10gtt/ml are as follows

Formula: ml infused/hours in minutesXdropfactor

250/60X10=2500/60

41drops per minute.

C) The drug is within safe parameters.

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