Question

PN 105 Fundamentals of Nursing I Aspirin - Peptic Ulcer PQ, a 72-year-old woman, has taken 650 mg of aspirin four times a day for 8 months to alleviate her symptoms of pain and inflammation associated with arthritis. Four weeks ago a peptic ulcer developed. 1. Explain the process in which PQ could have a peptic ulcer. How could this have been prevented? 2. Compare the similarities and differences in the side effects of salicylates with those of acetic acid agents, propionic acid agents, cOX-2 inhibitors, and phenylatic acid. 3. What patient teaching points should PQ receive before and during the time she takes the aspirin? 4. How would COX-2 prevent the development of a peptic ulcer? 5. Would DMARD's be more helpful in alleviating PQ's symptoms? Explain your answer. 6. Compare the differences in the various types of DMARD'S

Answer 1

1, Aspirin is a salicylate and NSAID drug to treat fever, pain, and swelling in case of arthritis. a peptic ulcer caused by bacteria or long term use of NSAID drugs. It makes ulcer by eroding mucus that coats the stomach lining, it interferes with natural defenses when contact digestive juices.
2, Salicyltes cause side-effects like abdomen pain, burning, bloody stools, ringing sensation the ear, headache, hives, vomiting with blood.
Acetic acid agents cause side-effects like hives, breathing difficulty, swelling of the face, throat, and lips, and burning sensation.
Propionic acid agents' side effects include headache, vertigo, lightheadedness, dizziness, hallucination, and depression.
COX2 inhibitors side effects include headache, nausea, diarrhea, rhinitis, abdomen pain, insomnia, dizziness, and rash
Phenylacetic acid side effects include skin, eye irritation, sore throat, and cough.
3, Advice patient to take aspirin with the correct dose as prescribed by the physician.
Take with adequate food and water.
Avoid alcohol and heavy drinks like soda when you take aspirin.
Keep it room temperature.
Never break or crush the tablet because enteric-coated pills avoid burning sensation or ulcer, it should take it as a whole.
See for the expiratory rate before taking
If you miss the dose skip it if it is time for the next dose, never overdose. If you overdose it call physician for help
Avoid medicines like ibuprofen, antidepressants, warfarin, herbal products, and vitamins, inform the doctor before taking it.
contact the doctor if you want to continue any other medications.
4, COX2 is an NSAID drug, it protects the gastric mucosal prostaglandin has a topical irritant effect. COX2 enzyme induced predominantly when inflammation occurs.