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Write the learnings and reflections about cancer immunology, critical appraisal tools, catmaker and EBM calculators in...

Write the learnings and reflections about cancer immunology, critical appraisal tools, catmaker and EBM calculators in 1000 words
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Answer: Cancer is characterized by common mutations and “ectopic” overexpression of many genes normally not expressed in the tissue of origin. These changes provide antigens that the adaptive immune system can recognize to differentiate the cancer cell from normal cells. Thus the immune system of a patient with cancer has the potential to selectively recognize their cancer. As soon as cancer develops they starts to eliminate antigens through further mutation.

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