Question

PN 200 Fundamentals of Nursing II Wound Infection - Amikacin JN, a 46-year-old woman, has a wound infection. The culture report stated that the infection was caused by Pseudomonas aeruginosa. JN's temperature was 102F at the time of the culture. Amikacin sulfate is to be administered IV in 100mL of DS/W over 45 minutes every 8 hours. The dosage is 15mg/kg/day in three divided doses, JN weighs 165 pounds. 1. What is the drug classification of the amikacin? 2. How many milligrams of amikacin should IN receive every 8 hours? 3. What type of IV equipment should be used for this infusion? 4. What would be the IV Infusion rate? 5. When would a wound culture be obtained to determine the appropriate antibacterial agent? Explain your answer. 6. What are the similarities of amikacin to other aminoglycosides? 7. Would one type of aminoglycosides be preferred over another? Explain your answer. The nurse assesses JN for hearing and urinary function before and during amikacin therapy 8. What should a hearing assessment include? 9. JN's urine output over the past 8 hours was 125 mL. Explain the possible cause for the amount of urine output. What nursing actions should be taken? 10. What laboratory tests monitor renal function? 11. The health care provider requests peak and trough serum amikacin levels. When should the blood samples to determine peak serum level and trough serum level be drawn? Reviewed 919

Answer 1

Question 1

Amikacin is a type of antibiotic drug that belongs to the class aminoglycoside drugs. This is a potent antibiotic agent that restricts the growth of bacteria.

Amikacin irreversibly binds to the 16S rRna and acts by changing the ribosomes shape and restrict the mRNA top read the codones correctly.

Question 2

As prescribed JN has to receive 15mg/kg/day dose of amikacin drug every day divided into the dose of three units. As seen JN weighs 165 pounds that is 75 Kg.

Step 1-

Total weight * 15 / 3

75 * 15 / 3

= 375mg amikacin is to be administered in every dose for 3 doses in a day.

Question 3

Administration of amikacin is done Intravenously that provides it slow infusion time. the apparatus required is IV cannulation, drip, difusion apparatus, and needle.

Question 4

The Intravenous line and apparatus is required to infuse amaikacin slowly over the infusion rate of 30 to 60 minutes.

(four answers are answered from the sub-parts as the guidelines please create new order for each question seperately)