Question

200 Fundamentals of Nursing II Wound Infection - Amikacin JN, a 46-year-old woman, has a wound infection. The culture report stated that the infection was caused by Pseudomonas aeruginosa. JN's temperature was 102F at the time of the culture. Amikacin sulfate is to be administered IV in 100mL of DS/W over 45 minutes every 8 hours. The dosage is 15mg/kg/day in three divided doses. JN weighs 165 pounds. 1. What is the drug classification of the amikacin? 2. How many milligrams of amikacin should IN receive every 8 hours? 3. What type of IV equipment should be used for this infusion? 4. What would be the IV Infusion rate? 5. When would a wound culture be obtained to determine the appropriate antibacterial agent? Explain your answer. 6. What are the similarities of amikacin to other aminoglycosides? 7. Would one type of aminoglycosides be preferred over another? Explain your answer. The nurse assesses JN for hearing and urinary function before and during amikacin therapy 8. What should a hearing assessment include? 9. JN's urine output over the past 8 hours was 125 mL. Explain the possible cause for the amount of urine output. What nursing actions should be taken? 10. What laboratory tests monitor renal function? 11. The health care provider requests peak and trough serum amikacin levels. When should the blood samples to determine peak serum level and trough serum level be drawn? Reviewed 919

Answer 1

1. The drug classification of amikacin is aminoglycoside antibiotics. It works by stopping the growth of bacteria.

2. Weight of the patient is 165 lbs = 74.25 kg

The odered dose of amikacin is 15mg /kg/day in three divided doses .

= 15× 74.25 = 1113.7

Dividing it into three doses = 113.7/3 = 371.2 mg per dose

371.2 mg of amikacin every 8 hourly .

3. Infusion pump should be used for this infusion

4. Infusion rate = Total volume /total time

Total volume - 100ml

Total time - 45mins = 0.75hrs

Infusion rate = 100ml / 0.75hrs

= 133.3 ml /hr