Question

PN 200 Fundamentals of Nursing II Wound Infection - Amikacin JN, a 46-year-old woman, has a wound infection. The culture report stated that the infection wa caused by Pseudomonas aeruginosa. JN's temperature was 102F at the time of the culture. Amikacin sulfate is to be administered IV in 100mL of D5/W over 45 minutes every 8 hours. The dosage is 15mg/kg/day in three divided doses, JN weighs 165 pounds. 1. What is the drug classification of the amikacin? 2. How many milligrams of amikacin should IN receive every 8 hours? 3. What type of IV equipment should be used for this infusion? 4. What would be the IV Infusion rate? 5. When would a wound culture be obtained to determine the appropriate antibacterial ag Explain your answer. 6. What are the similarities of amikacin to other aminoglycosides? 7. Would one type of aminoglycosides be preferred over another? Explain your answer. The nurse assesses JN for hearing and urinary function before and during amikacin the 8. What should a hearing assessment include? 9. JN's urine output over the past 8 hours was 125 mL. Explain the possible cause for of urine output. What nursing actions should be taken? 10. What laboratory tests monitor renal function? 11. The health care provider requests peak and trough serum amikacin levels. When blood samples to determine peak serum level and trough serum level be drawn?

Answer 1

1) Amikacin belongs to class of drug called aminoglycoside antibiotics. Used to prevent bacterial infections by stopping growth of bacteria.

2) 375mg / 8hrs

3) Intravenous administration - midline catheter IV

4) IV infusion rate is 12.5 mL/ hr

cal ilated by didvidng total volume / total time = ml/hr to infuse

5) wound culture be obtained after 3 days , so as to allow time for antibiotics to complete its action and to remove bacterial infections.

6) similarities of amikacina and other aminoglycoside like gentamicin, tobramycin,streptomycin are :

• potent bactericidal antibiotics
• act by inhibiting bacterial protein synthesis
• may cause nephrotoxicity
• action mostly against gram negative aerobic bacteria
• ineffective against anaerobic bacteria, fungi and virus,
• administration by intravenous or intramuscular method
• may cause sensoryneural hearing loss
• not used in myasthenia gravis patients