Task is to calculate sensitivity and specificity for each of the tests. D = Disease ND = No Disease Question 1 If you were most concerned about Sensitivity, which is the best screening test?When you might be most concerned about Sensitivity? If you were most concerned about Specificity, which is the best screening test?
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Homework Answers
ANSWER
Test A
D = 27, ND = 10
Sensitivity.
Formula = (True positives (TP) / (True positive(TP) + False negative(FN) ) * 100.
True positives = 27
False negative = 9
Sensitivity = (27 / (27 + 9)) 100
= 0.75 * 100
= 75%
Specificity
Formula =(True negatives(TN) / False positives(FP) + True negatives(TN)) * 100
True negative = 1
False positive = 0
Specificity = (1 / 0+1) 100
= 1 * 100
= 100%
Test B
D = 28, ND = 9
Sensitivity = (TP /TP+FN) * 100
TP = 28
FN = 8
= (28 / 28 + 8 ) 100
= 0.78* 100
= 78%.
Specificity = (TN / FP + TN) 100
TN = 1
FP = 0
= (1 / 0+1) 100
= 1* 100
= 100%
Test C
D = 35, ND = 2
Sensitivity =( TP /TP + FN ) 100
TP = 35
FN = 1
= (35 /35 + 1) 100
= 0.97.2 * 100
= 97.2%
Specificity = ( TN / FP + TN) 100
TN = 1
FP = 0
= (1 / 0+1) 100
= 100%
* Best screening test for sensitivity is Test C which giv4e more accurate information about
positive rate.
* More concern about sensitivity is because it help in probability of detection or measures
percentage of people who identified with disease.
* All three test are best for measure specificity or true negative rate.
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