1. The following reactions begin with starting materials of differing stereochemistry yet each provide the same...
1. The following reactions begin with starting materials of differing stereochemistry yet each provide the same stereoisomer of the product. Explain this observation using an arrow-pushing mechanism. Tsoo- сн,со, CH3CO2H CH,CO, CH3CO2H
For each of the following reactions, provide the product with proper stereochemistry if applicable. In addition, draw the arrow-pushing mechanism for the reaction. 1. CH HCI 2. CH HBr ROOR 3. CH, Н,0 H, SO 4. CH3 1. Hg(OA), 2. NaBH + 5. CH, 1. BH, THF 2. HO, NaOH
(10 points) Provide the Starting Materials/Reagents/Major Products for the following transformations. YOU MUST INDICATE STEREOCHEMISTRY AS NEEDED. (You may use asterisks to indicate an equal mixture of the two isomers at a given stereocenter). For each of these reactions, show a detailed arrow pushing mechanism (For problems b, c, and d, only show the first step of the mechanism) H.O. Me Me 1) BD, THF d) 2) D202 OD tBu e) Ch DCM
3. Provide the reagents necessary to carry out the following reactions or provide the starting materials or major products of the following reactions, Indicate racemic mixtures where necessary. (39 pts) 1)AIC осн, a. Ph 2) PaC H Н,со 45 1) HS0, HNO b. 2) Pd/c. H Н,со он c. Ph HO, он
1, Write detailed, arrow-pushing mechanisms for the following reactions. Predict the products when none are given. Н-о a) H2SO4 (cat.) CH3CO2H b) H2SO4 (cat.) CH,он c) H2SO4 (cat.) H2, Pd/C (no mechanism required) d) HCI e)
1. Provide the missing starting materials, reagents, or products in each of the following reactions. H+ OH CH,OH NaOH Meo NH2 room temp. HO OH Meo Me ОН Meo 2. Provide appropriate conditions to convert each of the following starting mana hexanoic acid (some transformations may require more than one step): It each of the following starting materials into OH OH ОMe "NH₂
3. Provide a full arrow-pushing mechanism for each of the following reactions. Wood CHAMBRE Cascos - LX i. CH3MgBr (excess) ii. H+ OH OCH; 4. Provide the major product of the following reaction and provide a mechanism for its formation. HO1 OH A 5. You need to synthesize a large amount of molecule C, and you have just enough of each of molecules A and B in your chemical inventory. Provide a synthetic route showing how you can efficiently synthesize...
Q2. Provide the missing information of the following reactions. (such as reagents, starting materials, products_etc.) 21 1. CH,CH-CH=PP 1-Propanol 2-methylpentan-3-one H+, heat H2N Н. + HO- Н HO- + Y. H trace HCI H НО. OH H3C сн. H30.4 H2CH2CO OCH CH3
6) Draw the starting materials required to make the following product. 5pts A fi 7) Provide the mechanism, including arrow pushing, for the following reaction. 2pts 8) Which of these dienes is capable of undergoing the Diels Alder reaction? 3pts 0.84 K 0$ D С
1. Propose a synthesis for either of the following molecules using the indicated starting materials. You don't have to use all of them, but all your carbon atoms must come from them alone. (Hint: A five membered lactone will spontaneously form from the correct hydroxy acid.) If you provide syntheses for both a 10 pt bonus will be awarded. OH со, КCN Br н Н NO, Br NH2 2. Propose a mechanism to account for the following reaction. Used the...