Question

What is the primary outcome measure?

What is the scale of the primary outcome measure?

The article is out out the New England Journal of Medicine

Bariatric Surgery versus Intensive Medical Therapy in Obese patients with Diabetes

Answer 1

The 5 year research had an outcome data which report that , among type 2 diabetes with a BMI of 27 to 43, bariatric surgery along with  intensive medical therapy was more effective than intensive medical therapy alone in some cases for resolving, hyperglycemia.

The outcome measure include following:

At end of 5 years, the urinary albumin-to-creatinine ratio (as measured in milligrams of albumin to grams of creatinine) had decreased significantly from baseline in the sleeve-gastrectomy group.

There was reductions in body weight, BMI, waist circumference, and waist-to-hip ratio were greater after gastric bypass and sleeve gastrectomy than after intensive medical therapy

The decrease from baseline in triglyceride levels and the increase from baseline in high-density lipoprotein (HDL) cholesterol levels were significantly greater at 5 years after the two surgical procedures than after intensive medical therapy.

The STAMPEDE trial at the end of 5 year, proved that bariatric surgery was superior to intensive medical therapy in terms of glycemic control, weight reduction, medication reduction, improvement in lipid level and quality of life.It was also made sure that , bariatric surgery along with intensive medical therapy gave better outcome