Question

for wer points ur kitt's Presentation lymphomia. Summarize the relevant facts of the case Consider the differential diagnosis Include lab data and indicate if the result is normal or abnormal If infectious decribe the causative agent agent. Describe the pathology of the disease Describe therapy and prognosis On the last slide indicate reference Use atation PPPP

Answer 1

BURKITT LYMPHOMA:

Burkitt lymphoma is form of hodgkins lymphoma where cancer starts in immune cells called beta cells. it is recognizes as fast growing human cancer. Burkitt lymphoma is named after British surgeon Denis Burkitt.

DIAGNOSIS:

If Burkitt lymphoma is suspected, all or part of an enlarged lymph node or other suspicious disease site will be biopsied. In a biopsy, a sample of tissue is examined under a microscope. This will confirm or rule out Burkitt lymphoma. Other tests incude: Chest X-ray, PET or gallium scan, Bone marrow biopsy, Exam of spinal fluid. Blood tests to measure kidney and liver function, Testing for HIV disease

PATHOLOGY:

One of the mechanism may be that malaria weakens the immune system's response to Epstein-Barr, allowing it to change infected B-cells into cancerous cells. About 98% of African cases are associated with Epstein-Barr infection.

INFECTION CAUSING AGENT:

Burkitt lymphoma is common in young children who also have malaria and epstein-barr, the virus that causes infectious mononucleosis.

TREATMENT:

Burkitt lymphoma can spread to the fluid surrounding the brain and spinal cord, chemotherapy drugs also may be injected directly into the cerebrospinal fluid, a treatment known as intrathecal chemotherapy. Some the drugs incuded are: cyclophosphamide (Cytoxan), cytarabine (Cytosar-U, Tarabine PFS), doxorubicin (Adriamycin), etoposide (Etopophos, Toposar, VePesid), methotrexate (Rheumatrex), vincristine (Oncovin)

PROGNOSIS:

Burkitt lymphoma is fatal if it is left untreated. In children, prompt intensive chemotherapy usually cures Burkitt lymphoma, leading to long-term survival rates of 60% to 90%. In adult patients, results are more variable. Overall, prompt treatment is associated with long-term survival rates of 70% to 80%.

REFERENCES:

•https://lymphoma.org/aboutlymphoma/nhl/burkitt

•https://www.webmd.com/cancer/lymphoma/burkitt-lymphoma-prognosis-diagnosis-treatments

https://www.healthline.com/health/burkitts-lymphoma