Question

STEREOSELECTIVE REDUCTION OF 4-tert-BUTYLCYCLOHEXANONE OH 1. NaBH4, EtOH 2. H30+ Cr TOH ity of nd to wiew ation vent. Introduction s must rongly LE TO emical Background reading to be read prior to the experiment: See the Chemistry 333L syllabus for reading material in the Chemistry 333 textbook. Pages 125-128 of this manual (Gas Chromatography.) Appendix VI: Operation of the Shimadzu GC-17A Gas Chromatograph. Appendix IX: Operation of the Perkin-Elmer 1600 Fourier-Transform Infrared Spectrophotometer. View the Gas Chromatography and Infrared Spectroscopy DVDs in the LRC, also lab A large number of hydride reagents reduce aldehydes and ketones to the corresponding primary and secondary alcohols, respectively. Two commonly used reagents are lithium aluminum hydride and sodium borohydride. Lithium aluminum hydride is a very reactive reagent and is quite dangerous. It reacts explosively with water. Sodium borohydride is a much less reactive reagent, yet is reactive enough to effect the reduction of aldehydes and ketones. Sodium borohydride will be used in this laboratory session it with h u n it in murah nafar to ung thon lithium aluminum hidrido Thir eyneriment focuses on ketone

just the balanced equations for main reaction and side reaction with steps and major / minor products please and thank you

can you create a balanced stereoselective mechanism equation for both reactions using the 4tertbutyl starting base equation from the 1st previous image for the primary reactions and side reaction equations on the 2nd previous image. and can you also include any major and minor products please and thank you

Answer 1

The t-butyl group is a bulky group, hence it occupies the equatorial position. the axial conformation is prsent in very less quantity. The hydride ion can attack from the top side or the bottom side of the axis. This gives rise to two products, one with an equatorial hydroxy group and another with an axial hydroxy group

H3C н: HC { о-вна Hąc Н.С. H3C Н.С. нс- нс ОН H₃c" НАС H3C нс