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How would the nurse educator explain the action of bivalirudin compared to heparin to their clinical...

How would the nurse educator explain the action of bivalirudin compared to heparin to their clinical group? Could you see concept mapping being used in this situation?

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Answer: The mechanism of action of bivalirudin as it inhibits the action of thrombin by binding to its catalytic site and to its anion-binding site. The action of bivalirudin is reversible because thrombin will slowly cleave the thrombin-bivalirudin bond which recovers the active site of thrombin.

Heparin acts by preventing cofactors such as thrombin and fibrin. By blocking the process early on, both warfarin and heparin reduce blood clots from forming in body.

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