Question

24-32 need help

carbons. Quite often one of those groups is hydrogen and the other is a good leaving group (LG) 24) Complete the following mechanistic step with three arrows. Use the table on page 1 if needed # -K.. PCW27 - Mechanistic steps - Part 1 Time spent 25) Describe the above arrow pushing in your own words. Nucleophilic Addition A nucleophilic addition involves the addition of a nucleophile top a polar pi bond. 26)Label the molecules below as a nudeophile or a polar pi bond. 27) Add the partial changes to the above molecules as you did before in part 5 and label as electron richo electron poor. Also, redraw the butyl lithium as the simplified carbanion species. (le, without the lithium 28) Which two carbon atoms would you predict to interact between the two molecules in part 267 Draw dashed line between them. 29) Propose a curved arrow mechanism to show the nucleophilic addition below. When the nucleophilic butyl anion attacks the carbon of the carbonyl the pi bond breaks and releases the electrons to the oxygen 30) What is the hybridization of the carbon of the carbonyl in the reactants? What is the hybridization of the same carbon in the products? Nucleophilic Elimination 2 The reverse of Nucleophilic Addition is Nudieophilic Elimination The result of nucleophilic elimination is the formation of a polar pi bond. 31) Complete the following reaction by adding the leaving group on the products side) and add curved arrows to show the flow of electrons. 10 0: Ka 32) What the overall charge on each side of the reaction? Is it balanced?

Answer 1

ons. 24 во. & H+ BH+ : LG Ans. 25 Base (80) attacks the most acidic proton. It attacks that preoton which is anti-periplanar to the Living Group (LG). This process is a dinuclear elimination reaction (E2). Fore Ez anti-orientation of H and LG is necessary.

shus. 26 OS 50 8 18 - Electrophile. ore polar pi-bond Nucleophile 88 dis. 2t 80 6 a Li electron rich This c-centree is election deficient.

Butyl corbanion Eston dis. 28 7+ Carbon caribonyl attached to i carbon corebon attached to Li and courbonyl courbon interrat with each other.

neat it shus. it Aus 29 compa When the nucleophile butyl anion attacks the carbon of the carbonyl the pi-bond breaks and releases the elections to the onygen. this. 30 The allo sp, hy dridied sp² hybridized Carbonyl carbon in reactant is sp² hybridized forbringt same Carbon in product is sp3 hybridized. Since no Thus

Lechcochemistry Ang : 31 Coco L + : +1+ Here the leaving group is ao dis. 32 Reactorunt side charge is -1 con amygen) Product side charge is 7 (on chlorine) Thus the reaction is charge balanced