How many regions of chromosome 6 with causative variants were identified in Schizophrenia?
Ans:4 different regions.
It is known that the MHC locus on chromosome 6 is a strong risk area.
McCarroll and colleagues explored on the particular region of the MHC with the highest GWAS score.and idenified the C4 gene
The C4 gene can exist in multiple copies (from one to four) on each copy of chromosome 6, and has four different forms: C4A-short, C4B-short, C4A-long, and C4B-long. These are the regions with causative factors for schizophrenia.
Supportive studies
How many regions of chromosome 6 with causative variants were identified in Schizophrenia?
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