Question

Case Scenario: A 75-year-old woman is taken to the ER following an incident where she is diagnosed with myxedema. Doctors quickly move her to the ICU, where she is monitored continuously for heart rate changes, changes in cognition, and level of consciousness. She appears to be cold and has decreased respirations, hypotension, and hypoglycemia.

Question: Explain the mechanisms primary and secondary hypothyroidism.

Answer 1

Primary hypothyroidism:

paimary hypothyroidiem Dr occus mainly due to the Dadequate function of the grand Diseld

Secondary hypothyroidism:

Secondary hypothyloidiam It occurs by of Thyroid stimulating boaňone adequate stimulation from pituitary

Mechanism of primary and secondary hypothyroidism:

Hypothalamus " TRH) pituitary gland (secondary lot TIH) hot T4& | Thyroid glina (primary 12 LT T3 1 Peripheral tissue/ Tu T

Primary - Destruction o Inflammation of Thyroid gland lead to decrease is production of Ty on To

secondary - pituitary gland dysfunction, leads to decrease Thyroid stimulating hormone