Aspirine can be synthesize by the reaction of salisylic acid with acetic anhydride mainly in strong acidic medium. In acidic medium one of the keto group of anhydride get protonated which facilitate the attack of -OH group to attack and reaction goes feasible.
For this protonation we mainly use strong acid. So phosphoric acid is also a strong acid like sulfuric acid which serve proton (H+) ion.
So the statement is - True
Phosphoric acid can be used instead of sulfuric acid in the synthesis of aspirin, O True...
1) In the lab of synthesis of aspirin, how will adding HCl instead of phosphoric acid affect the outcome of the experiment. 2) In the lab of synthesis of aspirin, what is the purpose of using KMnO4 solution? 3) Suggest 2 other ways(besides use of hickman still) that you can use to influence the direction of reaction equilibrium in the lab dehydration of alcohol to alkenes 4) How will the absence of hickman still affect the outcome of the experiment...
PRELAB EXERCISE EXPERIMENT 21 Synthesis of Aspirin (Acetylsalicylic Acid) What is the purpose of sulfuric acid or phosphoric acid used in the acetylation reaction? Use equations to explain this purpose. The procedure calls for cautious addition of water to the reaction mixture while it is still hot. What purpose does the addition of water serve and why should the addition be done while the reaction mixture is hot? Provide an equation for the reaction involved.Using the quantities of salicylic acid and acetic anhydride...
Synthesis of Aspirin Lab Quesitons 1. what major change in the IR spectrum would be expected upon conversion of salicylic acid to acetyl salicylic acid? 2. what purpose did the sulfuric acid serve in this reaction? what would happen if you used phosphoric acid, H3PO4 instead? 3. pick a prescription drug that you or your friends use. describe how it was synthesized
Question 16 What is the purpose of adding phosphoric acid in aspirin synthesis A) enhance the nucleophilicity of the OH of salicylic acid B) enhance the electrophilicty of acetic anhydride enhance the nucleophilicity of acetic anhydride D) enhance the electrophilicty of the carbonyl of salicylic acid А 8 С Question 17 Which statement(s) is correct for electrophilic aromatic substitution (EAS)? (multiple answer) ferrocene is more reactive than benzene A. benzene is more reactive than ferrocene B C. ferrocene is more...
2. a. Both concentrated sulfuric acid and concentrated phosphoric acid are known to catalyze the conversion of cyclohexanol to cyclohexene via dehydration reaction. Concentrated hydrochloric acid, however, is not a viable option. Provide two reasons on what make sulfuric acid and phosphoric acid advantageous over hydrochloric acid. Look up additional information on these acids if needed. b. In preparation of the bromohydrin (trans-2-bromo-1-methylcyclohexanol) with bromine, side products dibromides shown below are often observed. This side reaction can be essentially avoided...
One of the major uses of sulfuric acid is the production of phosphoric acid and calcium sulfate. The reaction is: Ca3(PO4)2(s) + 3H2SO4(aq) → 3CaSO4(s) + 2H3PO4(aq) What mass of concentrated sulfuric acid (98.0 % H2SO4 by mass) must be used to react completely with 155.9 g of Ca3(PO4)2?
Organic Chemistry Laboratory Work
Preparation of Acetylsalicylic Acid (ASPIRIN)
We used Sulfuric Acid for Quesiton 1.
1: What purpose does the acid in this experiment serve? 2: Why did you add water once the formation of aspirin is complete? 3: Why did you recrystallize the product from warm water?
Sulfuric acid is used in the synthesis and processing of many chemicals and metals, and it is the electrolyte in common lead-acid batteries. It is used in various strengths, ranging from concentrated (100%) to dilute; so being able to estimate its concentration from a simple measurement of specific gravity is quite useful. Suppose you prepare a solution that is 20 wt% H2SO4 in water and intend to confirm the concentration by comparing the specific gravity of the solution to that...
QUESTION 3 Salicylic acid reacts with acetic anhydride to form aspirin and acetic acid as shown. Use the equation to answer Questions 3 – 6. (salicylic acid) (aspirin) C7H6O3 (s) + C4H6O3 (l) → C9H8O4 (s) + CH3COOH (l) MM = 138 MM = 180 If we divide 180 by 138 we find that 1.00 g salicylic acid will produce a maximum of 1.30 g aspirin. 3. A student starts with 3.20 g salicylic acid. What is the maximum amount...
In the lab calledd Synthesis of Aspirin, the mass of salicylic acid is 3.037g , the mass of dried Aspirin finally is 2.793. What is the moles of salicylic acid used? What is the moles of aspirin expected? What is the mass of aspirin expected?