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Phosphoric acid can be used instead of sulfuric acid in the synthesis of aspirin, O True False
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Answer #1

Aspirine can be synthesize by the reaction of salisylic acid with acetic anhydride mainly in strong acidic medium. In acidic medium one of the keto group of anhydride get protonated which facilitate the attack of -OH group to attack and reaction goes feasible.

For this protonation we mainly use strong acid. So phosphoric acid is also a strong acid like sulfuric acid which serve proton (H+) ion.

So the statement is - True

n coolt COO 14 HO roa H₂ POq Hypoal of Acetic anhydride cool 0 o--CH3 CH.--oh Aspirine

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