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The causes of gastrointestinal cancer mutation are unclear, however identify and discuss three predisposing factors.

The causes of gastrointestinal cancer mutation are unclear, however identify and discuss three predisposing factors.

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*Age and Gender:

Most of the gastrointestinal cancer cases seen in the age above 55 years. It affects men twice when compared to women.

*Genetics:

Mutation of genes like BRCA1,BRCA2 and CDH1 have high risk of developing stomach cancer in their lifetime. HNPCC is associated with increased risk of colon cancer which is predisposing to stomach cancer.

*Lifestyle:

Smoking has linked with stomach cancer and smokers are more likely to get stomach cancer than nonsmokers. Some studies show that,processed meat can increase the risk of stomach cancer. Overweight and obesity are other risk factors for gastrointestinal cancer.

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