Cystic fibrosis is an autosomal recessive genetic disease of secretory epithelia that affect function of lungs which causes respiratory failure.It also affect other organs like liver, pancreas, small intestine, and sweat glands where the secretory epithelia is present in the body.
The effect of cystic fibrosis in lungs
Excess thick secretion of mucus and obstruction of airways are the main features of cystic fibrosis along with neutrophilic inflammation without any active infection. The impaired mucociliary clearance and increased viscosity of the mucus layer leads to mucus plugging and inflammation of the airways. This cause destruction of the lung tissue and difficulty in breathing. This reduce the capacity of lung tissue to take up oxygen during breathing which leads to decreased oxygen supply to the body organs or hypoxia( lack of oxygen in tissue level).
how Hypoxia and Cystic Fibrosis relate? Ho poxia and oystic foruss Reflection
how hypoxia and cyatic fibrosis relate? Ho poxia and oystic foruss Reflection
(3 parts for the answers) Cystic Fibrosis Cystic fibrosis is an autosomal recessive disorder that affects 1 in 3 000 newborns with a Caucasian background. It causes thick mucus build up in various organs and can cause damages and problems in respiratory and digestive systems. --What is the frequency of the cystic fibrosis allele in the Caucasian population? Show all your work and express your answer as a value between 0 and 1 rounded to two decimal places --What percentage...
An individual heterozygous for cystic fibrosis a) Will have children who are all carriers of cystic fibrosis. b) Cannot have children with cystic fibrosis. c) has cystic fibrosis d) is a carrier
Describe strategies to delete the Cystic Fibrosis gene and to replace a mutant Cystic Fibrosis gene with a fully functional gene in human cells using the CRISPR/Cas9 system.
The answer is e. I don't understand how to solve for it. Cystic fibrosis is a rare recessive genetic condition. Suppose that the allele that causes Cystic fibrosis has a frequency of 0.001 in a certain population. If the population can be assumed to be at Hardy Weinberg equilibrium approximately how many heterozygous carriers of the disease will be born for every individual born with the disease? 10 100 999 1000 1998
1. Describe the genetic defect in cystic fibrosis 2. How does the underlying genetic defect in cystic fibrosis lead to pulmonary and exocrine gland dysfunction?
Cystic fibrosis is an autosomal recessive disease caused by a mutation in a single gene with two alleles. Suppose the frequency of cystic fibrosis in a population is 3%. Assuming the gene is in HW equilibrium, calculate the allele and genotype frequencies. If the population consists of 100 individuals, how many are carriers (but unaffected) for the cystic fibrosis allele?
test is used for the diagnosis of cystic fibrosis.
Parents who do not have cystic fibrosis (recessive) produce a child who has cystic fibrosis. What are the chances that each child born to this couple will have cystic fibrosis? 100% 75% 25% 0% All of the choices are correct. Could a man with blood type A father a child with blood type B? No, only males with type B or AB can have children with type B blood. Yes, if his genotype was AO and the mother had type...
sean and michelle are healthy, but their daugher molly was recently diagnosed with cystic fibrosis. Guess the genotype of the parents for cystic fibrosis disease? a. sean and michele are heterozygous for cystic fibrosis allele, they are carreirs b. sean and michele are homozygous for cystic fibrosis allele, but the disease will be manifested later in their life c. sean does not have the cystic fibrosis allele, he is homozygous for the healthy variant of the gene, michell is the...