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SN 2: Mechanism: Br NaOH E2: Mechanism: Br NaOH 20 30 Methyl 1° Strong Weak 30...
When determining which mechanism (E1 or E2) occurs, the following process is helpful: 1) Determine the...
When determining which mechanism (E1 or E2) occurs, the following process is helpful: 1) Determine the substitution (methyl, 1º, 2º, or 3“) of the alkyl halide 2) Determine the strength of the nucleophile Please fill out the following table, indicating the category of reaction (E1 or E2) that will occur in each set of alkyl halides and nucleophiles. If no reaction occurs, write 'NR: Alkyl Halide Strong Base Weak Base Methyl 1° 20 3° For each of the following reactions,...
strong nucleophile weak base strong bulky base strong nucleophile strong base Promote SN2/E2 weak nucleophile weak...
strong nucleophile weak base strong bulky base strong nucleophile strong base Promote SN2/E2 weak nucleophile weak base Promote SN1/E1 Promote SN2 Promote E2 CH Br HS NCT HO CHO CHÚCHO NaNO NaOH NOME Noe HOORS Conjugate acids have pka 16-18 Conjugate acids Recall, you make hydroxide have pka 11 or alkoxide ons from the corresponding alcohol or water and Nat CH,OH (MOH) HO CH,CH,OH (EXOH) | HC-Ć-o to CH tert-BUOK NOCH KOHBU NEOBU The structures above are all ways of...
E1 and E2 Reactions: Predicted Ability: Good Average Poor Actual Ability: Good Average Poor When determining...
E1 and E2 Reactions: Predicted Ability: Good Average Poor Actual Ability: Good Average Poor When determining which mechanism (E1 or E2) occurs, the following process is helpful: 1) Determine the substitution (methyl, 1º, 2º, or 3º) of the alkyl halide 2) Determine the strength of the nucleophile Please fill out the following table, indicating the category of reaction (E1 or E2) that will occur in each set of alkyl halides and nucleophiles. If no reaction occurs, write 'NR:' Alkyl Halide...
2. (1.5 pts) Label the following reagents as Good or Poor Nucleophiles AND as Strong or Weak Base...
2. (1.5 pts) Label the following reagents as Good or Poor Nucleophiles AND as Strong or Weak Bases. OK Na SH 3. (1.5 pt) Predict the productts) of the following reactions, if there are multiple products indicate which, if any, is the major product. Be sure to clearly mark the stereochemistry of chiral carbon atoms and draw multiple products if there is more than one stereoisomer that forms. HCI MeOH H2SO H2 Pd/BaSO4 quinoline 4. (3 pt) For the following...
Please fill out the following table, indicating the category of reaction (Swi or Sm2) that will...
Please fill out the following table, indicating the category of reaction (Swi or Sm2) that will occur in each set of alkyl halides and nucleophiles. If no reaction occurs, write 'NR." Alkyl Halide Strong Nucleophile Weak Nucleophile SN2 SNZ SN2 SNI SNL SNU SNI SNI Methyl 10 2° 3° When determining which mechanism (Sw1 or S2) occurs, the following process is helpful: 1) Determine the substitution (methyl, 1º, 2º, or 3º) of the alkyl halide 2) Determine the strength of...
For each of the following reactions, determine which ELIMINATION mechanism (E1 or E2) will occur. Alkyl...
For each of the following reactions, determine which ELIMINATION mechanism (E1 or E2) will occur. Alkyl Halide Substitution: Methyl 1° 2° 3° Base Strength: Strong Weak Mechanism Type: E1 E2 Draw the mechanism that leads to ALL products for the reaction. Finally, underline the major product of the elimination reaction: H3C OH H2C H2C1 Br CHE
Propose a mechanism from the reaction in the box NaOH H,CH2CH.CH DMF Use the reaction for...
Propose a mechanism from the reaction in the box
NaOH H,CH2CH.CH DMF Use the reaction for 28-32 28. What is the classification of the alkyl halide? a.) methyl b.) 1° c.) 2° d.) 30 29. Is the base strong or weak? a.) Strong b.) Weak 30. Is the solvent protic or aprotic? a.) Protic b.) Aprotic 31. According to the base and solvent, which substitution mechanism will the reaction undergo? a.) SNI b.) SN2 32. The stereochemistry of the reactant...
Please help! for each reaction a)assess the substrate b) classify reagent (strong or weak; nuc or...
Please help!
for each reaction
a)assess the substrate
b) classify reagent (strong or weak; nuc or base)
c) solvent type if not indicated
d)mechanism type
e) major & minor products; proper stereochemestry &
geometry..
sn1,sn2,e1,e2
Lot (E2) O NÁSH (SN a NUC on Etoho Weak nuc Tb xs Nal XS Nal (SN22 H2O ignore Nuc/base effects of water weakbase good nuc tBuOK (potassium t-butóxide) strong Oa ge conc. H2SO4 30 heat elminator 6. но 7. DBN Br (strong base) -OEt...
How can you tell if a reactant, like the NaOH, is a strong/weak nucleophile or base...
How can you tell if a reactant, like the NaOH, is a
strong/weak nucleophile or base to determine what mechanism you
use? The picture provided has the correct answers. I just don't
understand how to get to them.
3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SN1, S2, E, or E2). E2 NaOH Н,0 CH3CH2ONa CH3CH2OH E2 CH2ONa иис CH3OH OCH3 Br CH3OH ИИ E1...
How can you tell what is a weak/strong nucleophile and a weak/strong base to determine what mechanism you use (SN1, SN2,...
How can you tell what is a weak/strong nucleophile and
a weak/strong base to determine what mechanism you use (SN1, SN2,
E1, E2)?
3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SNI, SN2, El, or E2). NaOH HO CH2CH ON CH3CH OH CHON CH,OH CH,OH DMSO
When determining which mechanism (E1 or E2) occurs, the following process is helpful: 1) Determine the substitution (methyl, 1º, 2º, or 3“) of the alkyl halide 2) Determine the strength of the nucleophile Please fill out the following table, indicating the category of reaction (E1 or E2) that will occur in each set of alkyl halides and nucleophiles. If no reaction occurs, write 'NR: Alkyl Halide Strong Base Weak Base Methyl 1° 20 3° For each of the following reactions,...
strong nucleophile weak base strong bulky base strong nucleophile strong base Promote SN2/E2 weak nucleophile weak base Promote SN1/E1 Promote SN2 Promote E2 CH Br HS NCT HO CHO CHÚCHO NaNO NaOH NOME Noe HOORS Conjugate acids have pka 16-18 Conjugate acids Recall, you make hydroxide have pka 11 or alkoxide ons from the corresponding alcohol or water and Nat CH,OH (MOH) HO CH,CH,OH (EXOH) | HC-Ć-o to CH tert-BUOK NOCH KOHBU NEOBU The structures above are all ways of...
E1 and E2 Reactions: Predicted Ability: Good Average Poor Actual Ability: Good Average Poor When determining which mechanism (E1 or E2) occurs, the following process is helpful: 1) Determine the substitution (methyl, 1º, 2º, or 3º) of the alkyl halide 2) Determine the strength of the nucleophile Please fill out the following table, indicating the category of reaction (E1 or E2) that will occur in each set of alkyl halides and nucleophiles. If no reaction occurs, write 'NR:' Alkyl Halide...
2. (1.5 pts) Label the following reagents as Good or Poor Nucleophiles AND as Strong or Weak Bases. OK Na SH 3. (1.5 pt) Predict the productts) of the following reactions, if there are multiple products indicate which, if any, is the major product. Be sure to clearly mark the stereochemistry of chiral carbon atoms and draw multiple products if there is more than one stereoisomer that forms. HCI MeOH H2SO H2 Pd/BaSO4 quinoline 4. (3 pt) For the following...
Please fill out the following table, indicating the category of reaction (Swi or Sm2) that will occur in each set of alkyl halides and nucleophiles. If no reaction occurs, write 'NR." Alkyl Halide Strong Nucleophile Weak Nucleophile SN2 SNZ SN2 SNI SNL SNU SNI SNI Methyl 10 2° 3° When determining which mechanism (Sw1 or S2) occurs, the following process is helpful: 1) Determine the substitution (methyl, 1º, 2º, or 3º) of the alkyl halide 2) Determine the strength of...
For each of the following reactions, determine which ELIMINATION mechanism (E1 or E2) will occur. Alkyl Halide Substitution: Methyl 1° 2° 3° Base Strength: Strong Weak Mechanism Type: E1 E2 Draw the mechanism that leads to ALL products for the reaction. Finally, underline the major product of the elimination reaction: H3C OH H2C H2C1 Br CHE
Propose a mechanism from the reaction in the box
NaOH H,CH2CH.CH DMF Use the reaction for 28-32 28. What is the classification of the alkyl halide? a.) methyl b.) 1° c.) 2° d.) 30 29. Is the base strong or weak? a.) Strong b.) Weak 30. Is the solvent protic or aprotic? a.) Protic b.) Aprotic 31. According to the base and solvent, which substitution mechanism will the reaction undergo? a.) SNI b.) SN2 32. The stereochemistry of the reactant...
Please help!
for each reaction
a)assess the substrate
b) classify reagent (strong or weak; nuc or base)
c) solvent type if not indicated
d)mechanism type
e) major & minor products; proper stereochemestry &
geometry..
sn1,sn2,e1,e2
Lot (E2) O NÁSH (SN a NUC on Etoho Weak nuc Tb xs Nal XS Nal (SN22 H2O ignore Nuc/base effects of water weakbase good nuc tBuOK (potassium t-butóxide) strong Oa ge conc. H2SO4 30 heat elminator 6. но 7. DBN Br (strong base) -OEt...
How can you tell if a reactant, like the NaOH, is a
strong/weak nucleophile or base to determine what mechanism you
use? The picture provided has the correct answers. I just don't
understand how to get to them.
3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SN1, S2, E, or E2). E2 NaOH Н,0 CH3CH2ONa CH3CH2OH E2 CH2ONa иис CH3OH OCH3 Br CH3OH ИИ E1...
How can you tell what is a weak/strong nucleophile and
a weak/strong base to determine what mechanism you use (SN1, SN2,
E1, E2)?
3. Draw a structural formula for the major organic product(s) of each reaction and specify the mechanism by which each product is formed (SNI, SN2, El, or E2). NaOH HO CH2CH ON CH3CH OH CHON CH,OH CH,OH DMSO
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