EtO2CCOEt HOC CO2Et porcine liver esterase BOCHN Ph BOCHN. Ph 1. CF3CO2H (TFA) 2. DCC 3....
1. NaOEt CO2Et 2. H30+ 3. heat Br. Br CORET + H3C V CO2H H₂C + CO2 + E H3C CO2Et The malonic ester synthesis is a carbonyl alkylation reaction. It is used to prepare carboxylic acids from primary alkyl halides, lengthening the carbon In progress by two atoms. Thus, the product can be visualized as being a "substituted acetic acid." The reaction consists of three steps: generation of the enolate anion followed by SN 2 reaction with a primary...
Need help on 6a and 6b. (Molecule 1&2, their pH and group are circled in blue) 6a. On the answer sheet, draw molecule 1 and molecule 2 (at the indicated pH) and also draw their conjugate bases. (For any molecules you do not know, look up the structure on google/wikipedia/text). Based on ionic stabilization effects, which molecule would have a lower pKa for the group listed? Explain in 2-3 sentences. b. timt-1 molecule l molecule 2 pH group phenylalanine l...