please help me with this pharmokinetics problem:
The study of a drug, after administration to experimental animals of 500 mg solution intravenously in the form of bolus, experimental data from the following table are obtained.
Time (hours) | Concenration (µg/mL) |
0.5 | 17.52 |
1 | 13.52 |
2 | 8.28 |
4 | 3.05 |
6 | 1.12 |
8 | 0.41 |
12 | 0.06 |
Calculate a) elimination constant, b) distribution volume, c) drug eliminationand clearance (in mL//min), d) area under the curve, e) the biological half-life of this drug
the given answers are: a)0.5 h-1 , b )22.2 L, c) 1.1 L/h, e)46.76 g*h/mL
please help me with this pharmokinetics problem: The study of a drug, after administration to experimental...
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