14. A 2 g dose of ampicillin given IV yields a blood level of 12 mcg/ml....
14. A 2 g dose of ampicillin given IV yields a blood level of 12 mcg/ml. The plasma elimination half-life of ampicillin is 30 minutes. If the minimal inhibitor concentration of ampicillin for E. coli is 1 mcg/ml, how long will the blood level of ampicillin be above the minimal inhibitory concentration (MIC)?
Homework Answers
Answer :
With a half life of 30 minutes and starting with bioavailability of 12 mcg/ml ,then after 30 minute the bioavailability is reduced to 6 mc/ ml then to 3 mcg/ ml after another 30 minutes etc ...
Ampicillin bioavailability will remain
above the minimal inhibitory concentration for approximately 1 hour 30 minutes to 1 hour 45 minutes.
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14. A 2 g dose of ampicillin given IV yields a blood level of 12
mcg/ml....
YOU ONLY NEED TO ANSWER QUESTIONS 1,5, & 8 AND…in addition to answering each question, state 2 other questions aft...
YOU ONLY NEED TO ANSWER QUESTIONS 1,5, & 8
AND…in addition to answering each question, state 2 other
questions after each of these that might be asked of you by a
health professional that would call on you to do the same
calculation, or know the same concept. Give answer for these, and
show all work.
174 Chapter LEARNING QUESTIONS (1) Gentamicin has an average elimination half- life of approximately 2 hours and an apparent volume of distribution of 20%...
7. Smokers are known to have about 50% higher CL than nonsmokers for theophylline. If the...
7. Smokers are known to have about 50% higher CL than nonsmokers for theophylline. If the average observed AUC after administration of 300 mg IV theophylline in nonsmokers is 100 mg.hr/L, what is the expected AUC in smokers after administration of the same 300 mg dose? Theophylline undergoes linear pharmacokinetics 2. After administration of a single 400 mg dose of a drug, a linear plot of the serum concentration-time prorile on a semi-log graph paper showed a y-intercept of 1mg/mL...
SECTION 1 CIinica! Calculations 2. Order: filgrastim 5 mcg/kg/day for myelosuppression secondary to chemotherapy administration Supply:...
SECTION 1 CIinica! Calculations 2. Order: filgrastim 5 mcg/kg/day for myelosuppression secondary to chemotherapy administration Supply: filgrastim 480 mcg/1.6 ml. Patient's weight: 100 lb 楽How many milliliters per day will you give? 3 4 STIM NDC 59513-34 m NEUPOGEN O Courtesy of Amgen, Indc. 16m PD2.1.1リリリリリ10,.12.,14 10 .20 30 40.50 .60 .70 80 .90 1.00mL 3. Order: Epogen 100 units/kg/day SQ three times weekly for anemia secondary to AZT administration Supply: Epogen 10,000 units/mL Patients weight: 180 lb ※ How...
HAPTER Three-Factor Medication Problems A Order ampicilin 100 mg/kg/day IV in divided doses every 12 hours...
HAPTER Three-Factor Medication Problems A Order ampicilin 100 mg/kg/day IV in divided doses every 12 hours for 169 respiratory tract infection Supply ampicillin 123 mg/s ml Neonate's weight: 1182 g s How many milligrams per dose will the neonate receive? How many milliliters per dose will you draw from the vial? 9. Order: Solu-Medrol 5.4 mgkghr IV for acute spinal cord injury Supply: Solu-Medrol 125 mg/2 ml Patient's weight: 160 lb ※ How many milligrams per hour will the patient...
1. An IV bag contains 600mg of a drug in 200mL of NS the flow rate...
1. An IV bag contains 600mg of a drug in 200mL of NS the flow rate in ml/h and the dosage rate in mg/min. 10 B of a drug in 200mL of NS, and must infuse over 2 hours. Find 2. An IVPB bag containing 50 mg of drug in 100mL of solution must intus 2mg/min. If the infusion begins at 0800 h, when will it finish? of solution must infuse at the rate of 3. ANIVPB IS infusing at...
O a. Blood urea nitrogen (BUN)-12 mg/dL b. Hemoglobin- 15 g/dL Oc. Platelet count-85,000 O d....
O a. Blood urea nitrogen (BUN)-12 mg/dL b. Hemoglobin- 15 g/dL Oc. Platelet count-85,000 O d. Potassium-4.2 mEq/ 16. Hydrocortisone (Solu-Cortef) 35 mg IM is ordered to treat inflammation. Hydrocortisone (Solu-Cortef) is available as 250 mg/10 mL. How many milliliters should be administered? O a.1 mL Ob.14 ml Oc.2 mL Od. 2.6 mL 17. The provider ordered a heparin bolus of 5,000 units IV followed by a heparin drip at 1,000 units per hour. The standard mixture of heparin is...
9 You are instructed to administer DiaBeta 3.75mg. The vial label reads DiaBeta 2.5mg per tab....
9 You are instructed to administer DiaBeta 3.75mg. The vial label reads DiaBeta 2.5mg per tab. How many tablets will you administer? 10. You are to administer Gantrisin 75 mcg and the tablets you have are labeled Gantrisin 0.15 mg. How many tablets will you administer? 11. You are instructed to give Tigan, 0.3g, IM. Your vial reads Tigan, 20 ml multiple dose vial, 100 mg/mL. How many mL will you administer? 12. You are instructed to add 0.75 g...
1. Glucophage 500 mg is ordered p.o. b.i.d. with breakfast and dinner. Pharmacy sends 1 g...
1. Glucophage 500 mg is ordered p.o. b.i.d. with breakfast and dinner. Pharmacy sends 1 g scored tablets of glucophage. How many tablet(s) will the nurse administer? _________ 2. The physician orders digoxin 125 mcg p.o. q.AM. Pharmacy sends digoxin scored tablets labeled 0.25 mg tablets. How many tablet(s) will the nurse administer to the patient? 3. Oxycontin 30 mg controlled-released tablet is ordered for the patient. The nurse has the following tablets available: Oxycontin 10 mg controlled-released tablet Oxycontin...
Dimensional Analysis Practice Set 3 1. The order reads: Hydralazine hydrochloride 10mg IM q.i.d. The strength...
Dimensional Analysis Practice Set 3 1. The order reads: Hydralazine hydrochloride 10mg IM q.i.d. The strength is 20mg/mL. How many milliliters of this antihypertensive will you a 2. Order: Heparin 4,000 units subcut a 12h. The label reads Heparin 5,000 Units per m in a 10mL multidose vial. How many milliliters will you administer? 3. The order: Neupogen 5mcg/kg subcut daily. The client weighs 200 pounds. There are two vials available; the strength in one vial is 480 mcg per...
phlebotomy 166 Unit Ill: Blood Collection Procedures MATCHING 9-4: SCENARIOS AND VASCULAR ACCESS DEVICES e type...
phlebotomy
166 Unit Ill: Blood Collection Procedures MATCHING 9-4: SCENARIOS AND VASCULAR ACCESS DEVICES e type of equipment described in the following scenaries with the list of vascular access devices. Scenarios Vascular Access Devices A nurse is collecting a blood gas specimen A. Arterial line (A-line) from tubing inserted in the underside of a B. Arteriovenous (AV) shunt patient's left wrist on the thumb side. C. Central venous catheter (CVC) D. Implanted port A nurse is palpating an area in...
YOU ONLY NEED TO ANSWER QUESTIONS 1,5, & 8
AND…in addition to answering each question, state 2 other
questions after each of these that might be asked of you by a
health professional that would call on you to do the same
calculation, or know the same concept. Give answer for these, and
show all work.
174 Chapter LEARNING QUESTIONS (1) Gentamicin has an average elimination half- life of approximately 2 hours and an apparent volume of distribution of 20%...
7. Smokers are known to have about 50% higher CL than nonsmokers for theophylline. If the average observed AUC after administration of 300 mg IV theophylline in nonsmokers is 100 mg.hr/L, what is the expected AUC in smokers after administration of the same 300 mg dose? Theophylline undergoes linear pharmacokinetics 2. After administration of a single 400 mg dose of a drug, a linear plot of the serum concentration-time prorile on a semi-log graph paper showed a y-intercept of 1mg/mL...
SECTION 1 CIinica! Calculations 2. Order: filgrastim 5 mcg/kg/day for myelosuppression secondary to chemotherapy administration Supply: filgrastim 480 mcg/1.6 ml. Patient's weight: 100 lb 楽How many milliliters per day will you give? 3 4 STIM NDC 59513-34 m NEUPOGEN O Courtesy of Amgen, Indc. 16m PD2.1.1リリリリリ10,.12.,14 10 .20 30 40.50 .60 .70 80 .90 1.00mL 3. Order: Epogen 100 units/kg/day SQ three times weekly for anemia secondary to AZT administration Supply: Epogen 10,000 units/mL Patients weight: 180 lb ※ How...
HAPTER Three-Factor Medication Problems A Order ampicilin 100 mg/kg/day IV in divided doses every 12 hours for 169 respiratory tract infection Supply ampicillin 123 mg/s ml Neonate's weight: 1182 g s How many milligrams per dose will the neonate receive? How many milliliters per dose will you draw from the vial? 9. Order: Solu-Medrol 5.4 mgkghr IV for acute spinal cord injury Supply: Solu-Medrol 125 mg/2 ml Patient's weight: 160 lb ※ How many milligrams per hour will the patient...
1. An IV bag contains 600mg of a drug in 200mL of NS the flow rate in ml/h and the dosage rate in mg/min. 10 B of a drug in 200mL of NS, and must infuse over 2 hours. Find 2. An IVPB bag containing 50 mg of drug in 100mL of solution must intus 2mg/min. If the infusion begins at 0800 h, when will it finish? of solution must infuse at the rate of 3. ANIVPB IS infusing at...
O a. Blood urea nitrogen (BUN)-12 mg/dL b. Hemoglobin- 15 g/dL Oc. Platelet count-85,000 O d. Potassium-4.2 mEq/ 16. Hydrocortisone (Solu-Cortef) 35 mg IM is ordered to treat inflammation. Hydrocortisone (Solu-Cortef) is available as 250 mg/10 mL. How many milliliters should be administered? O a.1 mL Ob.14 ml Oc.2 mL Od. 2.6 mL 17. The provider ordered a heparin bolus of 5,000 units IV followed by a heparin drip at 1,000 units per hour. The standard mixture of heparin is...
9 You are instructed to administer DiaBeta 3.75mg. The vial label reads DiaBeta 2.5mg per tab. How many tablets will you administer? 10. You are to administer Gantrisin 75 mcg and the tablets you have are labeled Gantrisin 0.15 mg. How many tablets will you administer? 11. You are instructed to give Tigan, 0.3g, IM. Your vial reads Tigan, 20 ml multiple dose vial, 100 mg/mL. How many mL will you administer? 12. You are instructed to add 0.75 g...
Dimensional Analysis Practice Set 3 1. The order reads: Hydralazine hydrochloride 10mg IM q.i.d. The strength is 20mg/mL. How many milliliters of this antihypertensive will you a 2. Order: Heparin 4,000 units subcut a 12h. The label reads Heparin 5,000 Units per m in a 10mL multidose vial. How many milliliters will you administer? 3. The order: Neupogen 5mcg/kg subcut daily. The client weighs 200 pounds. There are two vials available; the strength in one vial is 480 mcg per...
phlebotomy
166 Unit Ill: Blood Collection Procedures MATCHING 9-4: SCENARIOS AND VASCULAR ACCESS DEVICES e type of equipment described in the following scenaries with the list of vascular access devices. Scenarios Vascular Access Devices A nurse is collecting a blood gas specimen A. Arterial line (A-line) from tubing inserted in the underside of a B. Arteriovenous (AV) shunt patient's left wrist on the thumb side. C. Central venous catheter (CVC) D. Implanted port A nurse is palpating an area in...
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