1. We will be doing the following reactions. Draw the reactions as Snl or Sn2 reactions...
Answer both question 1 and 2. 1. We will be doing the following reactions. Draw the reactions as Sn1 or Sn2 reactions including reaction arrows. RER + Nal Run + NaBr... acetone RWY'R + NaBr(s) Et Refere nte Per + AgBros + HNO. EtOH AgNO3 R VR + AgBr(s) + HNO3 2. In your lab notebook draw the following table a. Rank each compound in terms of leaving groups, 1 = best and 10 = worst. b. Rank each compound...
please answer all parts Does 1-chlorobutane, an alkyl chloride, undergo a substitution reaction with the nucleophiles NaCl, NaBr, or Nal? Solubility data for each of these nucleophiles and the substrate is given in Table 1 below. Table 1: Solubility of Compounds in Various Solvents Compound Solvents in Which Soluble 1-chlorobutane Diethyl ether, hexanes, acetone, tetrahydrofuran NaCl Water, glycerol, ethylene glycol, formic acid NaBr Water, methanol Nal Water, ethanol, acetone 4. Write balanced chemical equations showing 1-chlorobutane undergoing a nucleophilic substitution...
please answer all parts Does 1-chlorobutane, an alkyl chloride, undergo a substitution reaction with the nucleophiles NaCl, NaBr, or Nal? Solubility data for each of these nucleophiles and the substrate is given in Table 1 below. Table 1: Solubility of Compounds in Various Solvents Compound Solvents in Which Soluble 1-chlorobutane Diethyl ether, hexanes, acetone, tetrahydrofuran NaCl Water, glycerol, ethylene glycol, formic acid NaBr Water, methanol Nal Water, ethanol, acetone 4. Write balanced chemical equations showing 1-chlorobutane undergoing a nucleophilic substitution...
1. Show the products of the following Sn2 reactions, including stereochemistry. Note: In all three cases, the solvent does not directly participate in the reaction (again, the solvents differ just so that the respective reactants all dissolve) and, as always, Nat is simply a spectator ion. a) EtOH Branche + NaOE EICH Hz + NaOEt acetone + Nal Phi Ph DMSO C YCHz + NaSH
1. Determine whether the following reactions go through SN or SNP and write the products, with stereochemistry as applicable. BrNHz NaOEt Nal OMS KCN CI DMSO Br HO NaSH DMSO Tso CH3 Nal Acetone CH3 2. The following reactions each undergo SNmechanisms. For each explain why you would predict the substitution products to come from an SN2mechanism and fill in the product. If stereochemistry is given in the reactants, give the correct stereochemistry in the products. Cl + Z Na...
7. Which of the following statements is TRUE? A) SN2 reactions occur with the same rate regardless of the structure of alkyl halide or substrate B) S2 reactions are concerted with no intermediate C) S 2 reactions proceed with the same rate regardless of the nucleophile used D) S2 reactions are best performed in polar protic solvents E) In an S 2 reaction, loss of the leaving group to give a carbocation is the rate-limiting step 8. Consider the following...
1. Determine whether the following reactions will go through SN1, SN2, E1, or E2 mechanism a. 1-bromobutane + sodium hydroxide b. 2-chloro-2-methylpentane + sodium hydroxide + heat C. 2,3-dimethyl-3-bromopentane + water d. 2-bromobutane + methanol 2. Draw the major product for the following reactions (draw both products if racemic): NaSH DMSO TsO CHA Nal CH, acetone CH,CH,ONa+ ethanol CH,OH/H-0 Solite Nal (1 equiv.) acetone F CH2CH OH 25°C
UNUN LILL 1. Describe the following chemical reactions as SNI. SN2. El & E. Draw a curved arrow mechanism for each reaction. KCN DMSO BE NaOH H20. heat 11 Br HO *** OH CHỊCH, Na* ethanol
1. (a) Draw the products for the following Sy2 reactions (0.5 pt ea) (b) Designate all asymmetric carbons as R or S (0.5 pt ea) CH3 OSOH + Bracetone P:EN: + , scelone, :OCH + Door NCCHE 2. (a) Draw the products for the following Syl reactions. (0.5 pt ea) (b) Designate all asymmetric carbons as R or Sor racemic. (0.5 pt ea) CH,OH - - - #20+ ytor - 3. (a) For the reactions below, predict the mechanism (Snl...
need help with the boxed bullet point. writing the chemical reaction scheme for the experiment. Synthesis of an Alkyl Halide: A Nucleophilic Substitution Reaction, Part I Pre-lab Assignment for Synthesis of an Alkyl Halide: A Nucleophilic Substitution Reaction, Part 1 1. From The Organic Chem Lab Survival Manual ( edition) by Zubrick • Review pages 201-204: Standard Reflux. • Review pages 127-140: Extraction • Review pages 164-189: Distillation, Simple Distillation. The Distillation Example, and The Distillation Mistake. 2. Read this...