The adult maintenance dosage for phenobarbital as an antiepileptic can be as great as 3 mg/day...
The adult maintenance dosage for phenobarbital as an antiepileptic can be as great as 3 mg/day for each kilogram of body mass. If the dose is administered by injecting a solution with a concentration of 130 mg/ml, how many milliliters are injected during the course of a day for an 86.67-kg patient?
Homework Answers
ANSWER.
* Calculation of volume(ml) of drug required.
Formula
Volume(ml) = Desired dose/Dose in hand * Quantity.
Here
Ordered dose = 3mg/kg/day.
Weight of the patient = 86.67 kg.
Desired dose(D) = 3 * 86.67
= 260.01 mg
Dose in hand (H) = 130 mg.
Quantity(Q) = 1 ml.
As per above formula
Volume(ml) of drug required = D/H * Q
= 260.01 / 130 * 1
= 2 * 1
= 2 ml / day.
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