Question

Metronidazole is used in the treatment of anaerobic protozoal infections. Although often administered orally, it can also be delivered by means of an IV infusion. The loading dose is 15 mg per kilogram of body mass and is infused over one hour. The maintenance dose is 7.5 mg per kilogram of body mass, is also infused over an hour, and is administered six hours after the loading dose. If the concentration of the metronidazole solution is 5 mg/ml, how many milliliters are required for a loading dose and three maintenance doses for a patient who weighs 220 pounds?

Paromomycin sulfate is used to eradicate intestinal amoebas. A typical dose consists of 35 mg/day for each kilogram of body mass. The treatment can last up to 10 days. For a patient who weighs 198 pounds, how many 250-mg capsules of paromomycin sulfate are required for a 10-day regimen?

Chloroquine is used to prevent or suppress malaria in patients. Two weeks before the patient is potentially exposed to malaria, and for six weeks after the patient has returned, chloroquine is administered once a week (on the same day) at a dose of 500 mg. Suppose the patient spends 13 weeks in an area in which there is high exposure to malaria. How many 250-mg tablets of chloroquine will be administered altogether?

Praziquantel is used to eradicate parasitic worms such as tapeworms. A one-day regimen consists of a dose of 60 mg for every kilogram of body mass. For a patient who weighs 154 pounds, how many 600-mg tablets of praziquantel are needed?

Answer 1

Solution -Aiven : Loading dose =Smalk Maintenance dose = 7.5m 2:20「 So, Loading dose köill be giver For 1 Maintenance dose Concentration Mehonidozole SmalmL 1 k 2ng So, For loacting clase Sma oduą is present in 1ml of Soluton | 496-6ma ol dnia hoill be byeent= }49.6-20.3 For. Maintenance dose - a 4812-149.64 mL for three maintenance dose 149.6 448,92 mL

Weight of polient9. o, 318m3142r126 tablets for Iday For lo day re(limen 12-6x10-126 tablets -g9.8 3 I 42, 85 mg dtay per 2Soma in 1 tablet

3 diven Soomg ber weak ojn 1 week we require 2 So x2 -Soomg That meant 2 tableks in one week Therefore bor 13h eeks= 2x13-26tables 2 20s So, 6om for f 69.gǔ x60mq= 4190.47 600mg in I tablet