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Metronidazole is used in the treatment of anaerobic protozoal infections. Although often administered orally, it can also be delivered by means of an IV infusion. The loading dose is 15 mg per kilogram of body mass and is infused over one hour. The maintenance dose is 7.5 mg per kilogram of body mass, is also infused over an hour, and is administered six hours after the loading dose. If the concentration of the metronidazole solution is 5 mg/ml, how many milliliters are required for a loading dose and three maintenance doses for a patient who weighs 220 pounds? |
Loading dose 15mg /kg
Maintenance dose 7.5mg/kg
Concentration of the medicine 5mg/ml
Weight of the patient 220 pounds = 99.7903kg (1pound = 0.453592kg)
So, loading dose for this patient 15* 99.79 = 1496.85mg
The solution should include 1496.85/ 5 ml = 299.37ml
Maintenance dose = 7.5mg/kg = 7.5* 99.79 = 748.425ml
The solution needed for the maintenance dose= 748.425/5 = 149.685ml
Metronidazole is used in the treatment of anaerobic protozoal infections. Although often administered orally, it can...
Metronidazole is used in the treatment of anaerobic protozoal infections. Although often administered orally, it can also be delivered by means of an IV infusion. The loading dose is 15 mg per kilogram of body mass and is infused over one hour. The maintenance dose is 7.5 mg per kilogram of body mass, is also infused over an hour, and is administered six hours after the loading dose. If the concentration of the metronidazole solution is 5 mg/ml, how many...
Metronidazole is used in the treatment of anaerobic protozoal infections. Although often administered orally, it can also be delivered by means of an IV infusion. The loading dose is 15 mg per kilogram of body mass and is infused over one hour. The maintenance dose is 7.5 mg per kilogram of body mass, is also infused over an hour, and is administered six hours after the loading dose. If the concentration of the metronidazole solution is 5 mg/ml, how many...
Metronidazole is used in the treatment of anaerobic protozoal infections. Although often administered orally, it can also be delivered by means of an IV infusion. The loading dose is 15 mg per kilogram of body mass and is infused over one hour. The maintenance dose is 7.5 mg per kilogram of body mass, is also infused over an hour, and is administered six hours after the loading dose. If the concentration of the metronidazole solution is 5 mg/ml, how many...
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A dose of methylnaltrexone bromide is administered to patients weighing over 251 lbs at a level of 0.15 mg per kilogram of body mass. Each dose is administered through a subcutaneous injection every other day. If a patient weighs 264 lbs and the methylnaltrexone bromide solution has a concentration of 20 mg/ml, how many milliliters will be administered in a period of two weeks?
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