1. (20 pts) Give the structure of the major organic product (including stereochemistry if appropriate) formed...
Predict the major product expected in each of the following reactions. Clearly show stereochemistry in your drawing, if applicable. ŞOH H2SO4 (diluted) heating 1CH,CHSCVAICI, 2) Zn(Hg)/HCI он BryFeBry ထိ Sot KMnO4 H, heat CH3CCI Meo -NO2 AICI, 1) Fuming H2SO4 2) SOCI AICI
11. Draw the structure of the major organic product of the reaction sequence below. (4 marks) Show all mechanistic steps and intermediates. ОН Y i) SOCI, ii) CH, AICI: iii) Zn(Hg). HCI, heat
3. (24 pts) Provide the structure(s) of the major product formed in the following reactions. Be sure to show any significant stereochemical details. (a) 2 1. -OH,H,O 2.H,O", heat (b) ci AICI (C) SH HS H H,SO -OH 1. Na,Cr,O, H,SO4 2. SOCI, pyridine 3. excess (CH,CH2)2NH excess (e)
3 (24 pts) Give the structure of the major organic product of each of the following reactions, including stereochemistry where appropriate. NaOH methanol-water Он CH-CECH 1. (Sia),BH 2. H,O NaOH OTs NaBr Acetone (OTs Tosylate) NaCN ethanol-water OH Na,Cr,O, H,SO, H,O I н.о H,SO Bra он FeBr NaBH Ethanol
1. (15 pts) Give the structure of the major organic product formed in each of the following reactions. H, (1 atm) HC-CEC-CHE- Lindlar Catalyst HCI HAC-CEC-CH. Large Excess CI HAC-CEC-CH3 - 1. (Sia), BH HyC-CEC-CH3 2. H,O,, NaOH (Sia),BH BrHCEC Na NH, (liu)
Provide the major organic product (including stereochemistry if appropriate) for each of the following reactions: 3. 1) NaH а) (CH)-СHCH,ОН 2) (CH),СНОСH-CH,Br b) excess HI 1) Hg(OAc),/H,O 2) NaBHĄ/HO¯ 1) NaOH 2) PҺOH d) CH,CH,Br 1) BH3/THF 2) H-0,/Но" НCIZnClz он g) MCPBA h) 1) mCPBA 2) CH3O¯ 1) mCPBA 2) CH,ОН/Н"
Give the major organic product from each of the following reactions (including any appropriate stereochemistry): 1. (10) Give the major organic product from each of the following reactions (including any appropriate stereochemistry): HBr H20 2 ) O 3 2) H 2O2 1) BH 3 2) NaOHH H20 2 CH ,OFH 3 heat CH3 Br NaOCH 3
2. Reactions: (27 pts) Draw the structure of the expected organic product(s) formed in the following reactions including correct stereochemistry, if the product is racemic indicate this by either drawing both enantiomers or drawing one and writing racemic. Assume all reagents listed are present in excess unless otherwise noted. If no reaction occurs, state No Reaction'. H, Pd/C Cl2, hv A) Br CH, OH B) CH3CH2CH2OH H2SO4 D NaBH, CH3CH2OH SOCI TEA H OTS CH,SNa DMSO OH F) OH PCC...
4. (15) Predict the major organic product, including any appropriate stereochemistry, for each of these reactions: NaSH H 2 Pi > 1) BH 3 2) NaOH, H202 n g hanisms to explain these transformations:
2. Reactions: (27 pts) Draw the structure of the expected organic product(s) formed in the following reactions including correct stereochemistry, if the product is racemic indicate this by either drawing both enantiomers or drawing one and writing racemic. Assume all reagents listed are present in excess unless otherwise noted. If no reaction occurs, state 'No Reaction'. Ha, Pd/C Cl2, hv A) Br CH, OH B) CH3CH,CH, OH H2SO4 D) NaBH "H CH,CH, OH SOCI TEA OTS E) CH SNa DMSO...