From the above mentioned products, acid, amide, ester, and acid anhydride can be synthesized with acyl substrate with nucleophillic reagent while acid chloride cannot be synthesized by this way.
therefore answer is acid chloride
20. Which of the following cannot be made from the others by nucleophilic acyl substitution? a....
Which of the following is least reactive during nucleophilic acyl substitution reaction? a. amide b. anhydride c. ester d. acyl chloride e. none of the above
The following amide is synthesized from an acid chloride via nucleophilic acyl substitution. Draw the two neutral organic starting materials needed to synthesize the amide. сна
The following amide is synthesized from an acid chloride via nucleophilic acyl substitution. Draw the two neutral organic starting materials needed to synthesize the amide. . H3C CH3 H
Paragraph Styles 6. ... 7 1. Why is an ester less reactive to nucleophilic acyl substitution than an acid chloride? A) Chloride is a better leaving group B) Oxygen is better at donating electron density into the carbonyl with added resonance stability. C) Chloride is a better leaving group and compared to chlorine, oxygen is better at donating electron density into the carbonyl with added resonance stability D) The alkoxy anion is less basic than the chloride anion. 2. What...
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Name: Total 100 pts (25X4 pts) 1) Which of the following is the best name for the following compound? A) 1,2-Dichloropentanal )1-Chloro-1-butanecarbonyl chloride C) 2-Chloropentanoyl D) 1-Chloropentanoyl chloride 2) Which of the following is the best name for the following compound? 0 a) tsobutyl ethanoate d) Ethoxy isobutyl ketone b) Ethyl isopropanoate c) 3-methylbutyl ethanoate e) Ethyl 3-methylbutanoate 3) Which compound would have highest pKa? E) D) B) A) 4) Which of the following would be the strongest acid?...
Time Ela Attempt d 26 Minut 2.5 pts D Question 8 Which of the following funtionalities would contain the best leaving group for nucleophilic acyl substitution? ester amide Carboxylic acid anhydride
Questions 12-20 are true and false!
(12) Hydrolysis of nitriles is a method to synthesize carboxylic acid. (13) The order of reactivity of carboxylic acid derivatives is as follow: Acyl chloride > Acid anhydride > Ester > Amide. (14) SOCI2, PC13 and PCls are three types of special reagents to convert carboxylic acid to acyl chloride (15) Acyl chlorides are the most reactive common acyl derivatives, and can be used to synthesize anhydride, ester, and amide. (16) Acyl chloride is...
Rank the following carbonyl-containing
compounds in order of reactivity towards nucleophilic acyl
substitution.
Rank the following carbonyl-containing compounds in order of reactivity towards nucleophilic acyl substitution Most reactive Least reactive butyl acetate benzoic anhydride 3-methylpentanoyl chloride propionamide
Which of the following is NOT a derivative of a carboxylic acid? ester acyl chloride amide aldehyde
Please answer all questions
6) Identify the correct IUPAC systematic name for the structure below. who -CH H A) N-methyl-2-ethyl-5-methyloctanamide B) 6,N-dimethylnonane-3-carboxamide C) 5,N-dimethyl-2-ethyloctanamide D) 2-ethyl-5,N-dimethyloctanamide 7) Which of the following is the most reactive carboxylic acid derivative? A) ester B) anhydride C) nitrile D) acid chloride E) amide 8) Identify the carboxylic acid derivative/s in the structure of Lactimidomycin. HN OH O A) Ester B) Anhydride C) Nitrile D) Imine 9) Arrange the carboxylic acid derivatives below in order...