Question

39. An IV infusion order is received for aminophyline 500mg in 500mL of D5W, to be infused at 1mg/kg/hr. The patient weighs 154 lbs. What will the flow rate be in mL/min? a) 1.2 mL/min b) 2.2 mL/min c) 3.2 mL/min d) 4.2 mL/min
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Answer 1

The correct option is a) 1.2 ml/min

The given infusion is 500mg aminophylline in 500ml D5W.

The concentration of the infusion is (weight of drug / volume of infusion )

which is (500mg/500ml) = 1 mg/ml

Weight of the patient is 154 pounds

2.2 pounds equals to 1 kg approximately

154 pounds = (154/2.2) kg

which is 70kg approximately.

Required infusion rate is 1 mg/kg/hr

for 70 kg patient, it is = 70 mg/kg/hr

Flow rate per one hour is 70 ml/hr

as one hour = 60 minutes

flow rate per minute = ( flow rate per hour / 60 )

It is 70/60 = 1.167 ml/min which is approximately 1.2 ml/min.

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