Question

1. Compare and contrast first and second generation antihistamines. Discuss at least one medication of each type. Include the indications, side effects, and any patient teaching.
2. Discuss decongestants including the difference between nasal and systemic decongestants. Include the action, administration/route, side effects, and drug interactions/considerations. List at least one decongestant medication.
3. Discuss the different types of antitussives, including the pharmacokinetics while discussing at least one antitussive.

Answer 1

Antchestomines - frist Generation generation Inhibit acteunity of H, Receptors ... Cross Blood Brein berries treat allergic reactions & I to little extent mest cell seleted disorders 1 - Have folessed effect - cross had train barrier on periphered histamine receptors - eg. diphenhydramicie, dosyleine -induce drowsiness - reduce internation go atrisine . Cetrisine - med to relieve . . Common cold, treners allergy symptons like side effecti- sedation, increased heart | watery eyes reny * hele pupil deletion delenium) 1. hose, sneezing Lines teachin Krinaky betertion sa side effects include Roys Should not be taken if allergic to / stomach pain, drowsy this medicine - Be careful while trining - Avoid alkoholu Scannekeln medicine out of reach CamScanroof children Diphenhydromene Indications-treet allergies, insonnie

Teachings (Cetrinne) - Insult physician if you have wondron deffrey 1 Kidney disease, his discese . foid alcold or other list drugs. - Bm7 druie we machinery - Consult it pregnancy is there/ suspected Decagettanto drug to relieve rosal congestion in upper respiratory treat infections: Nasal deengestants , Septemic decongestano - ausilable in nesel 1 hanger meet of Action sa drops / sprogs - Has Local action - mirinize syptenic absorption sige effect: Burning, Stinging, sneezing , l . pseudoephedrine. a hasd dripess. life effects increases . es prenylephrine, haphasoline heat hele stad pressure, Argine haorsening yerostimee diephoresis, reusee procide no inmediate relief - No Rebound masodilation - No local irritation g. phenylpropanolamine Scanned with Carcanner

Antitussives g reducing actvity of tough - Suppress coughing Center in brein Types: Nareste - effective in suppressing tough reflex -Lead to dependence g. codeine . Pharmacokinetics of codene ( anarcotic drugs. -Less effective - G. Dex from othorphan Bensonetate sille effets: Headache, chocsiness, Constipation, , itching Absuptron GI tract : لحيت دارد صhex distribution and tissues as 7-287. bound to plasma proteins Metabolism: 70-80). By liver Elimination : 90.). By kedrags cstall Leferithe 3hours. scanner