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Discuss the different types of antitussives, including the pharmacokinetics while discussing at least one antitussive. Write...

Discuss the different types of antitussives, including the pharmacokinetics while discussing at least one antitussive.

Write an NCLEX style question on either type of medication discussed. Include the answer and rationale.  

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Answer #1

Antitussives are the agents which helps in the suppression of cough. (Cough centre suppressants)

A) opioids : codeine, ethylmorphine,pholcodine

B)nonopioids : noscapine,dexteomethorphan,chlophedianol

C) antihistamines: chlorpheriramine,diphenhydramine ,promethazine

While discussing one antitussives with its pharmacokinetics:

Dextromethorphan:- a synthetic central NMDA (N methyl D aspartate) receptor antogoanta; the d isomer has antitussive action while y isomer is analgesic.the antitussive action of dextromethorphan is somewhat equivalent to codeine.

Pharmacokinetics:- after oral consumption it is absorbed in gastrointestinal tract and then enters to blood stream and crosses the blood brain barrier.

In gastrigastrointe tract it is converted into active metabolite dexteophan in liver.elimination half life is approximately 4 hours .duration of action is about 3-8 hours.

# question related to antitussive:

Anna is having her pharmacilpha exam tommarow .she should be aware that antitussive are used for :-

a) to encourage removal of secretions through coughing

b) control a productive cough

c)relieve rhinitis

d)relieve a dry cough

And: relieve a dry cough

An antitussive is a cough suppressant.choice A and B describe the action of an expectorant. Choice C describes the action of a decongestant.

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