Question

Which of the following are true of somatropin? 1. It is also known as growth hormone. 2. It is also used for wasting associated with human immunodeficiency virus (HIV) 3. It should be used for any child who is of short stature. 4. Its use may cause hypoglycemia and hyperglycemia. 5. Variations in its secretion may lead to acromegaly in adults and dwarfism in children. A. 1,2, and 3 B. c. D. 1, 2, 4, and 5 2, 3, and 5 1, 2, 3, 4, and 5 RONam

Answer 1

      Somatropin is a growth hormone important for growth of muscles and bones.It helps to treat growth failure in children and adults who lack natural growth hormone.It is a small protein that is produced by pituitary gland and secreted into the bloodstream.This growth hormone is controlled by a set of hormones produced in hypothalamus of the brain, intestinal tract and pancreas.It is produced at night than during the day.Growth hormone acts on many tissues throughout the body.

      Somatropin is used to treat HIV in people.It is secreted by the anterior pituitary gland, used to strengthen muscles which leads to disruption of growth hormone in HIV patients.It also helps to boost up their immune system.

   The glucose balance in circulation is maintained by regulation of both glucose production from liver and kidney. Insulin,the primary regulator of glucose balance,lowers postprandial glucose by increasing glucose uptake.Glucagon and epinephrine prevent hypoglycemia and decrease glucose uptake.

Acromegaly is a disorder that occurs when pituitary glands releases too much growth hormone into the body over a long period of time.This can even leads to a condition called gigantism.It begins before end of puberty, when children's growth plates fuse or close.When growth hormones enters blood, it gives signal to liver to produce another hormone which causes bones and body tissues to grow.The high levels of this can affect blood glucose and lipids leads to type 2 diabetes, high blood pressure and heart disease