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If you contrast case control study and randomized clinical trial, which could be the advantages and...

If you contrast case control study and randomized clinical trial, which could be the advantages and disadvantages of each one? Please elaborate your answer and provide references.

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Answer #1

ANSWER :

* ADVANTAGES OF CASE CONTROL STUDY :

- Case control study is beneficial in studying of human population

- They are time consuming and low cost

- They are useful for study of rare diseases  

DISADVANTAGES OF CASE CONTROL STUDY :

- They are based on selection bias

- They do not calculate incidence rates

- Inefficient for rare exposures

* ADVANTAGES OF RANDOMIZED CLINICAL TRIAL :

- Obtained results are analyzed with known tools

- Participating individuals are identified clearly

- They act as a good randomization

DISADVANTAGES OF RANDOMIZED CLINICAL TRIAL :

- They are very expensive

- Population participation will not be whole all the time

- Lack of follow up to treatment

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