Question

• b.Describe the effect of metabolic acidosis on respiration and on the central nervous system.
• c.In an elderly person with respiratory acidosis due to chronic respiratory congestion, why would decreased kidney function be so dangerous?
• d.If serum pH decreases to 7.1 because of severe renal disease, explain the change that has occurred in the buffer pair and the effect of this change on the central nervous system.
• E.Explain why sublingual administration is faster than oral administration.
• F.How would severe kidney or liver damage affect blood levels of a drug?

Answer 1

The metabolic acidosis atfect rechiroton as the incraied carbon diozide tension of the blood 9 depleHhon o bicarbonate causes on incree the depth ond then the rate o respnathion by cfimulafion of reapiratoy Center he metabolic acidosis allect cental Nervous System s eeck of severe hybercorbia include lethar and stuporat Plo 60 mtor more, coma oecurs ah pCo2 of 9o mn an elderly percon oith rabirahory acidats due to chronic respiratory eve con getion, decrease unction is longenus becaute the lungs are failing Co then it goes douon ompensa fion to Compensate Serum pH dereae to 71 because of severe enal disease, the change hat has occurred In the bafter fair mplie Hat the hydrogen content has been increated, meanin decreased. In the cenhal nervous system, the change leach to delay In eading o halluunahons and n the bcarbonate has processing oh inbomatio may ead to letorgic re sponuer