In order to determine if the patient with the blood results shown here could complete glycolysis,...
In order to determine if the patient with the blood results shown here could complete glycolysis,
what substance would you test for in her blood?
|
Blood Metabolic Panel |
|
|
Blood Glucose |
+ |
|
Glucose-6-phosphate |
++ |
|
Fructose-6-phosphate |
++ |
|
Fructose-1,6,bisphosphate |
++ |
|
Glyceraldehyde-3-phosphate |
++ |
|
1,3-bisphosphoglycerate |
++ |
|
Phosphoenolpyruvate |
++ |
|
Pyruvate |
- |
|
ATP |
- |
|
Red Blood Cell Concentration |
- |
|
A. Pyruvate |
||
|
B. Pyruvate kinase (enzyme that preceeds Puruvate) |
Homework Answers
Glycolysis: It is the principle route for carbohydrate metabolism.. Pathway takes place in all cells of the body. It is the only pathway which can operate aerobically and anaerobically
Irreversible steps of glycolysis are:
1.Hexokinase.
2.phospofructokinase.
3.pyruvate kinase .
In the given scenerio all the steps of glycolysis are completed except last step that is conversion of phospoenol pyruvate to pyruvate which is catalized by pyruvate kinase here ATP is generated.
It will be due to pyruvate kinase deficiency: In pyruvate kinase deficiency, total ATP generated will decrease to 50%. RBC will tend to gain calcium, lose pottasium and water. This leads to hemolysis and anemia.
There will be two to three folds of elevation in 2,3 BPG level due to blockage of conversion of phospho enol pyruvate to pyruvate. The increase of 2,3 BPG will moderate the effects of anemia by favouring unloading of oxygen to the tissues.
Thus we need to test for 2,3 BPG level in blood.
Add Answer to:
In order to determine if the patient with the blood results
shown here could complete glycolysis,...
To answer this question, you may reference the Metabolic Map. Select the steps of glycolysis in...
To answer this question, you may reference the Metabolic Map. Select the steps of glycolysis in which ATP is produced. glyceraldehyde 3-phosphate — 1,3-bisphosphoglycerate fructose 6-phosphate fructose 1,6-bisphosphate glucose + glucose 6-phosphate phosphoenolpyruvate - pyruvate 1,3-bisphosphoglycerate → 3-phosphoglycerate Suppose 19 glucose molecules enter glycolysis. Calculate the number of inorganic phosphate molecules required as well as the number of pyruvate molecules produced. pyruvate =
Tautomerization of enolpyruvate to pyruvate occurs in step 10 of glycolysis. If DG°’ = -46 kJ/mol,...
Tautomerization of enolpyruvate to pyruvate occurs in step 10 of glycolysis. If DG°’ = -46 kJ/mol, what is the ratio of pyruvate to enolpyruvate at equilibrium? Steady-State Concentrations of Glycolytic Metabolites in Erythrocytes Metabolite mM Glucose 5.0 Glucose-6-phosphate 0.083 Fructose-6-phosphate 0.014 Fructose-1,6-bisphosphate 0.031 Dihydroxyacetone phosphate 0.14 Glyceraldehyde-3-phosphate 0.019 1,3-Bisphosphoglycerate 0.001 3-Phosphoglycerate 0.12 2-Phosphoglycerate 0.030 Phosphoenolpyruvate 0.023 Pyruvate 0.051 Lactate 2.9 ATP 1.85 ADP 0.14 Pi 1.0
Rank from the first to the last steps to describe the correct order of events of...
Rank from the first to the last steps to describe the
correct order of events of glycolysis.
Rank from the first to the last steps to describe the correct order of events of glycolysis. Reset Help Glyceraldehyde- 3-phosphate COOP 3-phosphoglycerate ooo ATP This reaction happens Glucose-6-phosphate OOOOOO Rearrangement P + ADP Glucose GOOOOO NAD* - Fructose-16-bisphosphate POOOOOO twice, once ADP for each glyceraldehyde- 3.phosphate bisphosphoglycerate OOOP + NADH Fructose-6-phosphate ССССССР 2-phosphoglycerate This GOO reaction happens Rearrangement twice, once Phosphoenolpyruvate for...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
1. Diagram the process of sucrose breakdown into glucose and fructose and submit as an image. Use...
1. Diagram the process of sucrose breakdown into glucose and
fructose and submit as an image. Use Worksheet 7 to illustrate this
process (Show structures and enzymes. Include any key
intermediates).
2. Diagram the process of fructose is metabolized into
glycolysis in adipose tissue and submit as an image. Use Worksheet
7 to illustrate this process (Show structures and enzymes. Include
any key intermediates)
3. Diagram the process of fructose is metabolized into
glycolysis in liver tissue and submit as...
please explain answer Glycolysis. In the third step of glycolysis, the enzyme phosphofructokinase transfers a phosphate...
please explain answer
Glycolysis. In the third step of glycolysis, the enzyme phosphofructokinase transfers a phosphate group from ATP to fructose-6-phophate to generate fructose- 1,6- bisphosphate. In contrast, in step 10, the enzyme pyruvate kinase transfers a phosphate group from phosphoenolpyruvate to ADP to generate ATP. Using what you know about the standard free energy change associated with phosphate bonds, (briefly) explain why we observe this difference.
1. 2. 3. 4. Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate...
1.
2.
3.
4.
Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
I am confused with this glucose structure, Can you answer the question asked on the right...
I am confused with this glucose structure, Can you answer the
question asked on the right side of the page, please?
Glucose Hexokinase ATP Glucose 6-phosphate Phosphoglucose isomerase Fructose 6-phosphate Phosphofructo- ATP kinase-1 ADP Dihydroxyacetone phosphate Fructose 1,6-bisphosphate Aldolase Triose 5 phosphate Glyceraldehyde isomerase 3-phosphate (2 molecules ) Glyceraldehyde 2 NAD+ +2P, 3-phosphate 2 NADH + 2H dehydrogenase I 1,3-Bisphosphoglycerate (2 molecules) 7 Phosphoglycerate 2ADP kinase 2 ATP 3-Phosphoglycerate (2 molecules) Phosphoglycero- mutase 2-Phosphoglycerate (2 molecules) Enolase. > 2H2O Phosphoenolpyruvate...
12/25 answered Click on glycolysis if would like to review it in details. Glucose Preparatory phase...
12/25 answered Click on glycolysis if would like to review it in details. Glucose Preparatory phase first ATP Phosphorylation of glucos and its conversion to glyceraldehyde 3-phosphat Priming © > ADP Glucose 6-phosphate 1-0 Hz Hexokinase ΝΟΗ Η e Phosphohexose isomerase Fructose 6-phosphate ATP (8 Phospho- fructokinase-1 primins и он -OCH, CH-OH HOH он и ©--CH, CH-0- Кинон Aldolase ADP Fructose 1,6-bisphosphate (6) Triose phosphate somerase eleava oferte suar phosphate to two carbon sur phosphate Glyceraldehyde 3-phosphate udehyde a phosphate...
To answer this question, you may reference the Metabolic Map. Select the steps of glycolysis in which ATP is produced. glyceraldehyde 3-phosphate — 1,3-bisphosphoglycerate fructose 6-phosphate fructose 1,6-bisphosphate glucose + glucose 6-phosphate phosphoenolpyruvate - pyruvate 1,3-bisphosphoglycerate → 3-phosphoglycerate Suppose 19 glucose molecules enter glycolysis. Calculate the number of inorganic phosphate molecules required as well as the number of pyruvate molecules produced. pyruvate =
Rank from the first to the last steps to describe the
correct order of events of glycolysis.
Rank from the first to the last steps to describe the correct order of events of glycolysis. Reset Help Glyceraldehyde- 3-phosphate COOP 3-phosphoglycerate ooo ATP This reaction happens Glucose-6-phosphate OOOOOO Rearrangement P + ADP Glucose GOOOOO NAD* - Fructose-16-bisphosphate POOOOOO twice, once ADP for each glyceraldehyde- 3.phosphate bisphosphoglycerate OOOP + NADH Fructose-6-phosphate ССССССР 2-phosphoglycerate This GOO reaction happens Rearrangement twice, once Phosphoenolpyruvate for...
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
1. Diagram the process of sucrose breakdown into glucose and
fructose and submit as an image. Use Worksheet 7 to illustrate this
process (Show structures and enzymes. Include any key
intermediates).
2. Diagram the process of fructose is metabolized into
glycolysis in adipose tissue and submit as an image. Use Worksheet
7 to illustrate this process (Show structures and enzymes. Include
any key intermediates)
3. Diagram the process of fructose is metabolized into
glycolysis in liver tissue and submit as...
please explain answer
Glycolysis. In the third step of glycolysis, the enzyme phosphofructokinase transfers a phosphate group from ATP to fructose-6-phophate to generate fructose- 1,6- bisphosphate. In contrast, in step 10, the enzyme pyruvate kinase transfers a phosphate group from phosphoenolpyruvate to ADP to generate ATP. Using what you know about the standard free energy change associated with phosphate bonds, (briefly) explain why we observe this difference.
1.
2.
3.
4.
Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate ~2-phosphoglycerate 1) fructose-6-phosphate→ fructose-1,6-bisphosphate . glucose glucose-6-phosphate Select all that apply. Alcohol fermentation: consumes ATP as it produces ethanol. O produces carbon dioxide begins as pyruvate is decarboxylated to acetaldehyde in a reaction catalyzed by alcohol dehydrogenase m regenerates NAD requires the enzyme alcohol dehydrogenase, In the figure below, what is the reaction occurring at the location...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
I am confused with this glucose structure, Can you answer the
question asked on the right side of the page, please?
Glucose Hexokinase ATP Glucose 6-phosphate Phosphoglucose isomerase Fructose 6-phosphate Phosphofructo- ATP kinase-1 ADP Dihydroxyacetone phosphate Fructose 1,6-bisphosphate Aldolase Triose 5 phosphate Glyceraldehyde isomerase 3-phosphate (2 molecules ) Glyceraldehyde 2 NAD+ +2P, 3-phosphate 2 NADH + 2H dehydrogenase I 1,3-Bisphosphoglycerate (2 molecules) 7 Phosphoglycerate 2ADP kinase 2 ATP 3-Phosphoglycerate (2 molecules) Phosphoglycero- mutase 2-Phosphoglycerate (2 molecules) Enolase. > 2H2O Phosphoenolpyruvate...
12/25 answered Click on glycolysis if would like to review it in details. Glucose Preparatory phase first ATP Phosphorylation of glucos and its conversion to glyceraldehyde 3-phosphat Priming © > ADP Glucose 6-phosphate 1-0 Hz Hexokinase ΝΟΗ Η e Phosphohexose isomerase Fructose 6-phosphate ATP (8 Phospho- fructokinase-1 primins и он -OCH, CH-OH HOH он и ©--CH, CH-0- Кинон Aldolase ADP Fructose 1,6-bisphosphate (6) Triose phosphate somerase eleava oferte suar phosphate to two carbon sur phosphate Glyceraldehyde 3-phosphate udehyde a phosphate...
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