Ans 1 : Fructose-6-phosphate to Fructose-1,6-biphosphate
The build up of ATP in the cells or body inhibit the action of enzyme phosphofructokinase that catalyses the rate limiting step in glycolysis to convert Fructose-6-phosphate to Fructose-1,6-biphosphate. When the body is already rich in ATP , it does not need anymore energy so the breakdown of glucose must be prevented . The ATP binds to the enzyme PFK at its allosteric site and inhibit its action to halt the glycolysis process.
1. 2. 3. 4. Select all that apply. Identify the reaction(s) of glycolysis inhibited by ATP □ glyceraldehyde-3-phosphate → 1,3-bisphosphoglycerate phosphoenolpyruvate +pyruvate 3-phosphoglycerate...
In glycolysis, how is glyceraldehyde 3 phosphate converted to 1,3 bisphosphoglycerate? Pils used to provide phosphate ATP is used to provide phosphate Phosphate is transferred from fructose 2,6 bisphosphate NADPH provides the phosphate This reaction does not occur in glycolysis, the question is invalid D Question 8 During anaerobic conditions ... (Select all that apply) Glycolysis risks failing due to lack of a key metabolite. NADH is consumed. Lactate dehydrogenase ceases to function. Pyruvate Dehydrogenase Accelerates. Question 9 Given the...
GLYCOLYSIS Glucose-8 phosphate + Glucose 2 Fructose-6-phosphate 3 Fructose-1,6-biphosphate Dihydroxy-acetone-phosphate 5 Glyceraldehyde-3-phosphate VT6 2 (1,3-biphosphoglycerate) 7 3-phosphoglycerate 2-phosphoglycerate 9 phosphoenolpyruvate 10 Lactate Pyruvate Which two reactions of glycolysis requires an investment of ATP energy, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which two reactions of glycolysis generate energy in the form of ATP, and which enzyme catalyzes each reaction? Reaction Number Enzyme Reaction Number Enzyme Which glycolytic reaction generates energy in the form of NADH,...
35) The overall reaction of glyceraldehyde 3-phosphate dehydrogenase (GAP glyceraldehyde 3-phosphate + NAD+ + P = 1,3-bisphosphoglycerate + NADH GAPDH couples together two reactions with favorable (AG'°-50 kj/mol) and unfavorable (AG' +50 kJ/mol) Gibbs free energies, respectively. a) (6 pts) Write the balanced chemical equations for the two separate reactions. b) (6 pts) Draw the structure of the thiohemiacetal intermediate and show the mechanism for generating the acyl thioester intermediate. 36) (4 pts) Under anaerobic conditions, lactic acid fermentation regenerates...
1) Which of the following glycolysis intermediates can be generated from glycerol? dihydroxyacetone phosphate 1,3-bisphosphoglycerate glyceraldehyde-3-phosphate 3-phosphoglycerate 2) Which of the following is the oxidizing agent in the reaction that converts succinate to fumarate? FAD, NADH, NAD+, succinate, Coenzyme A, or FADH2 3) Five NADH molecules in the mitochondria can be made into _____ number of ATP.
1. You have given all the enzymes and intermediates in glycolysis. Choose the right enzymes and intermediates and draw the glycolytic pathway. Decorate the diagram by adding ATP, ADP, H", NADH, NAD', P, and H20 where necessary. All the steps are reversible except 1, 3 and 10; draw appropriate arrow. First arrange the reactants in the correct order. Reactants/intermediates: 3-phosphoglycerate glucose Phosphoenolpyruvate dihydroxyacetone phosphate Pyruvate glucose 6-phosphate 1,3-bisphosphoglycerate fructose 6-phosophate 2-phosphoglycerate glyceraldehyde 3-phosphate fructose 1,6-bisphosphate Enzymes: Phosphoglucoisomerase phosphoglycerate kinase phosphoglycerate...
Glycolysis activity 1: Metabolic pathway puzzle Try to complete the activity without using the textbook. 1. Slides 4 and 5 show the 10 reactions for glycolysis, but some of the molecules are missing. Draw the missing molecules in the proper place (on the handout). The missing molecules are shown on the next slide, you have to use the clues on the handout and your organic chemistry knowledge to figure out where each molecule belongs. 3. In the red dotted boxes...
The reaction glyceraldehyde-3-phosphate + NAD++Pi→ 1,3 diphosphoglycerate + NADH+H+ has ΔrG∘′=6.3kJmol−1. If the standard reduction potential ε∘′ of NAD+ is -0.324 V and the reaction 1,3 diphosphoglycerate + ADP→ 3-phosphoglycerate + ATP has ΔrG∘′=−18.8kJ/mol, calculate the standard reduction potential ε∘′ for the reaction 3-phosphoglycerate +2e−+3H+→ glyceraldehyde-3-phosphate +H2O.
2) if a single glucose molecule was completely catabolized to 2 pyruvate, then the liver built the 2 pyruvate back to glucose, how much free energt would be lost? 4) at which glycolysis metabolite does glycogen synthesis amd the pentose phosphate pathway branch off from? MIBROS JUJILOR DUE 3/13 at the beginning of class CHOH ресто points) OPOCH HO PHY OH OR equal ts3 > Loc Energy 50 Investmen when Phase n ] ohuoc but at Glucose 1)(6) Fill in...
ve the overall reaction ATP + glucose→glucose-6-phosphate + ADP + H. lf the &G" of ATP hydrolysis is /mol, what is AG for the coupled reaction? A. 46 kJ/mo B-18.4 kJ/mol C. -32.2 kJ/mol D. 18.4kJ/mol 26. Which of the following is true about oxidation-reduction reactions? A. B. C. D. During oxidation a compound gains electrons. Every oxidation must be accompanied by a reduction Dehydrogenases typically remove two electrons and two hydrides (H). There are four commonly accessed oxidation states...
Evaluate the reactions shown below, and select all true statements that apply. 2 ADP + 2 2 ATP c=0 Glucose Glycolysis сн. 2 Pyruvate 2 NAD 2 NADH 2 CO2 2 H CH H-C-OH + CH, 2 Ethanol (a) Alcohol fermentation 2 Acetaldehyde A. Glucose is the reducing agent B. NADH is being reduced. C. NAD+ is being reduced. D. Acetylaldehyde is being oxidized. E. Acetylaldehyde is the oxidizing agent F. As pyruvate is converted to acetyaldehyde, pyruvate is reduced...