. Given the information above, where does mevastatin bind on the enzyme? where does mevastatin bind...
Homework Answers
ANS) The Mevastatin is commonly known as the cholesterol reducing factor which is separated from the penicillium citinium ( fungus).The mevastatin minimizes the hepatic formation of the cholesterol for lessening the possibilities of heart problems. Mevastatin usually binds on coenzyme A part in active site.
Usually the Mevastatin aggressively hold back(discourage) the HMG-CoA reductase and this obstruction will stop the rate limiting level in the cholesterol unification.The reduced hepatic cholesterol range will leads to enhanced absorption of LDL or Low Density Lipoprotein cholesterol and will decline the cholesterol range in flow.
The aftereffects of Mevastatin are stomach pain,myalgias and vomiting.But other than this there are many other serious side effects for Mevastatin connected to hepatotoxicity and and myopathy.And because of its serious aftereffects,it is not provided medically.
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. Given the information above, where does mevastatin bind on
the enzyme?
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