Ans) 38) b. Up
Explaination:
- In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus. The complementary process that involves increases of such components is called upregulation
39) b. Transcription, translation, cell signaling
Explaination:
- Protein synthesis: consists of two processes — transcription and translation. In eukaryotic cells, transcription takes place in the nucleus. During transcription, DNA is used as a template to make a molecule of messenger RNA (mRNA). The molecule of mRNA then leaves the nucleus and goes to a ribosome in the cytoplasm, where translation occurs. During translation, the genetic code in mRNA is read and used to make a protein. These two processes are summed up by the central dogma of molecular biology: DNA → RNA → Protein.
Transcription
Transcription is the first part of the central dogma of molecular
biology: DNA → RNA. It is the transfer of genetic instructions in
DNA to mRNA. During transcription, a strand of mRNA is made to
complement a strand of DNA.
Translation
Translation is the second part of the central dogma of molecular
biology: RNA → Protein. It is the process in which the genetic code
in mRNA is read to make a protein. Translation is illustrated in
the diagram below. After mRNA leaves the nucleus, it moves to a
ribosome, which consists of rRNA and proteins. The ribosome reads
the sequence of codons in mRNA, and molecules of tRNA bring amino
acids to the ribosome in the correct sequence.
Cell signaling:
- Cells have proteins called receptors that bind to signaling molecules and initiate a physiological response. Because membrane receptors interact with both extracellular signals and molecules within the cell, they permit signaling molecules to affect cell function without actually entering the cell.
40) d. Denaturing
Explaination:
- Denaturation is what happens when heat is applied to the eggs. The heat coming from your stove denatures the protein by disrupting some of its bonds that held the molecule into shape. In the case of hard-boiled eggs, the proteins clump together and solidify, causing the egg white and yolk to harden.
-regulation is used to describe the "turning on" of protein synthesis by cell signaling. 38. The...
QUESTION 18 Following activation of a mitogenic signaling pathway, which of these events occur to promote cell division? a. Dephosphorylation of Retinoblastoma protein. b. Increased expression of p21. c. Phosphorylation of Myc. d. Inhibition of new protein synthesis. 1 points QUESTION 19 The slow rise of S cyclin levels throughout G1 phase is due to ___________, and the abrupt decrease is caused by ___________. a. import; export b. synthesis; mitosis c. transcription; proteolysis d. phosphorylation; translation
Question 19 (1 point) Which of the following steps is not associated with protein synthesis? a) Initiation b) Transcription c) Replication d) Translation Question 20 (1 point) A nucleic acid is a) DNA or RNA. b) a base pair. c) a nucleotide.
In what part of the cell does the Translation phase of protein synthesis occur? A. nucleus B. cell wall C. mytochondria D. cytoplasm
You are interested in cell size regulation and discover that signaling through a GPCR is important in controlling cell size in rat white blood cells. The G protein downstream of this receptor activates adenylyl cyclase, which ultimately leads to the activation of PKA. You find that cells that lack the GPCR are 15% smaller than normal cells, whereas cells that express a mutant, constitutively activated version of PKA are 15% larger than normal cells. Furthermore, the normal blood cells become...
2. The following is a description of a signaling pathway initiated by receptor tyrosine kinases. Ligand → RTK → Sos → Ras → Raf → MEK → ERK → Transcription factor → Cell growth A. (3pts) Which of these steps indicates the protein is activated after a GTP exchange step? B. (3pts) Which of these proteins can be deactivated by phosphatases? C. (4pts) Describe a mutation that would cause Ras to be permanently "on"? Would this mutation lead to high...
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32. Study the signaling pathway illustrated below, which involves two different receptors. Assume that a protein is active only when it is activated, but not inhibited, by its upstream signaling molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively. Assume that the transcription regulator can be activated by either the binding protein or the kinase that are immediately upstream of the transcription factor. Under which of the following conditions will the expression of target:gene "X" be induced?...
Zithromycin inhibits protein synthesis in bacteria. However, it cannot cross gram-negative bacteria cell walls. Would you expect zithromycin to be broad or narrow spectrum? Why? Amphotericin B disrupts the plasma membrane by binding to sterols. Why can’t it be used to treat bacterial infections? Match the following processes with the statements listed below. (Answers may be used more than once.) a. transcription b. translation c. DNA replication Ciprofloxacin inhibits DNA helicase. Which process is inhibited? _______________ RCT is a nucleotide substitute for uracil. Which process is inhibited? ___________ Tetracycline...
If a eukaryotic cell has synthesized a large quantity of a certain protein, you would know that all of the following had occurred prior to protein formation, except: A. Repressor proteins were likely bound to all of the enhancer sequences and proximal elements of the gene for this protein. B. A transcription initiation complex was formed at the promoter region of the gene for this protein. C. Chromatin remodeling occurred in the region of the chromosome containing this gene for...
A cell that is heterozygous for a nonsense mutation in a tumor suppressor gene would most likely: A) Group of answer choices B) grow but not divide C) have a normal cell cycle D) arrest and induce apoptosis E) have a slightly increased cell cycle and increased cell growth F) grow and divide uncontrollably Which of the following correctly describes an event that occurs during transcription: Group of answer choices A) A DNA molecule is chemically modified to become a...