In stabalizing selection :
1. How is the relative fitness of genotypes affected when selection is acting against homozygotes?
2. What effect does it have on the mean phenotype and genotypic/phenotypic variation within a population?
In disruptive selection
1. How is the relative fitness of genotypes affected when selection is acting against heterozygotes?
2. What effect does it have on the mean phenotype and genotypic/phenotypic variation within a population?
How do mutation rate and/or selection coefficients affect the equilibrium frequency of deleterious alleles?
In stabalizing selection : 1. How is the relative fitness of genotypes affected when selection is...
For each of the following mechanisms (a-h), consider how it will affect genetic diversity (i.e., diversity of alleles) within a population and select one of the following three options that best describes this effect: (i) increase/maintain, (ii) eliminate, or (iii) no effect [No written explanation necessary]. a. Positive frequency dependent selection b. Negative frequency dependent selection c. Selection in favor of a dominant phenotype d. Selection in favor of a recessive phenotype e. Selection favoring heterozygotes over homozygotes f. Mutation...
Consider a locus with two alleles - B and b. B is dominant, while b is recessive. There is no mutation. B has a selective advantage relative to b, so that the fitnesses of the three genotypes are BB = 1, Bb = 1, and bb = 1-s. In this case, s = 0.50, so that bb homozygotes have 50% fitness of heterozygotes and BB homozygotes. If the population has the following genotypic counts prior to selection of BB =...
Sickle-cell anaemia is an example of how fitness depends on environmental conditions. In places where malaria, caused by Plasmodium falciparum is common, HbAHbS heterozygotes have a selective advantage compared to individuals who are homozygotes for the wild type allele. However, HbSHbS homozygotes suffer from sickle-cell anaemia and usually die before producing offspring. The relative fitness (w) of the three genotypes in Nigeria are: HbAHbA 0.78, HbAHbS 1.0 HbSHbS 0.07 a. What is the mathematical relationship between relative fitness and selection...
2. Which of the following correctly describes how inbreeding will affect genotype and allele frequencies in Hardy-Weinberg populations? Genotype and allele frequencies will be unaffected. The frequency of heterozygotes will decrease, but allele frequencies will be unaffected. The frequency of homozygotes will increase, and deleterious alleles will decrease. Beneficial alleles will increase in frequency, as well as the genotypes containing those alleles. Genotype frequencies will return to H-W expectations after 1 generation of random mating. 3. Consider a population with...
Question 1 Which of the following is NOT true regarding Hardy-Weinberg equilibrium (HWE)? Most real species will not be at HWE at all loci within their genome If a locus has genotype frequencies consistent with HWE, then the species as a whole is not evolving If a locus has genotype frequencies consistent with HWE, then no evolution is occurring at that locus If a locus does NOT have genotype frequencies consistent with HWE, then some form of evolution is occurring at that locus Question 2 Which of...
The relative fitness (w) of three genotypes are wAA=1, wAa=1, and waa=0.5, indicating that the waa genotype has fitness that is only 50% as high as the fitness of the wAA and wAa genotypes. A population starts with p=0.7 and q= 0.3, where p and q are the frequencies of the A and a alleles, respectively. What will be the value of p in the next generation, following one round of selection? Important information regarding your calculations: please provide an...
1) In Dar es Salaam, Tanzania in the early 1950's, 24% of adults were found to be sickle-cell heterozygotes; the rest were normal homozygotes. No homozygotes for the sickle-cell allele were found, presumably because all such individuals had died in childhood. A) What was the frequency of the sickle-cell allele among adults in this population? (Note: the adults are not in Hardy-Weinberg proportions). B) Assuming that the population was in equilibrium under heterozygote advantage, and taking the relative fitness of...
heterozygote disadvantage Natural selection is the process by which organisms with the best adapted phenotype are selected for by environmental conditions. anthropogenic events such as the use of DDT heterozygote advantage Allelic frequencies can change due to selection or they may change due to genetic drift. environmental conditions The process of natural selection relies on the presence of of a gene within a population. genetic drift Deleterious alleles may persist in the population particularly if they confer a single allele...
Selection for insecticide resistance is very strong, Curtis et al. estimated the relative fitness in the mosquito, Anopheles culicifacies, an important vector for malaria in Asia. They estimated the finesses of the three genotypes, SS, SR and RR (S is susceptible, and R is resistant) under exposure to the insecticide DDT based on the assumption that resistance is dominant. 12pts Relative Fitness: Species Insecticide SS SR RR Anopheles culicifacies with DDT 0.35 1.0 1.0 without DDT 1.0 0.83 0.65...
The relative fitness of three genotypes at a particular locus are W11=0.65, W12=0.75, W22=0.9. Four populations have the following set of allele frequencies. In which population will the change in allele frequencies (due to selection) be the most rapid? (Show work) CLEAR hand writing or typing A. p = 0.86 & q = 0.14 B. p = 1.0 & q = 0.0 C. p = 0.05 & q = 0.95 D. p = 0.49 & q = 0.51